Gene: PNRC2
Official Full Name: proline rich nuclear receptor coactivator 2provided by HGNC
Gene Summary: Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in Golgi apparatus; P-body; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14999 | PNRC2 Knockout cell line (HeLa) | Human | PNRC2 | 1:3~1:6 | Negative | Online Inquiry |
KO15000 | PNRC2 Knockout cell line (HCT 116) | Human | PNRC2 | 1:2~1:4 | Negative | Online Inquiry |
KO15001 | PNRC2 Knockout cell line (HEK293) | Human | PNRC2 | 1:3~1:6 | Negative | Online Inquiry |
KO15002 | PNRC2 Knockout cell line (A549) | Human | PNRC2 | 1:3~1:4 | Negative | Online Inquiry |
PNRC2 Gene Knockout Cell Lines are highly specialized biological tools designed to facilitate the study of the PNRC2 gene, which encodes a protein implicated in various cellular processes, including gene regulation, RNA metabolism, and cellular stress responses. These knockout cell lines are generated using state-of-the-art CRISPR-Cas9 technology, effectively creating a precise deletion of the PNRC2 gene, thereby allowing researchers to explore the functional consequences of PNRC2 loss in a controlled environment.
The primary mechanism of action involves the targeted disruption of the PNRC2 gene, resulting in the absence of its protein product. This gene knockout allows for the examination of cellular phenotypes, signaling pathways, and gene interactions that depend on PNRC2 functionalities. By elucidating these mechanisms, researchers can uncover the role of PNRC2 in various biological processes, which is crucial for understanding disease pathology and potential therapeutic targets, particularly in cancers and neurodegenerative disorders.
The scientific importance of PNRC2 Gene Knockout Cell Lines extends across both research and clinical settings. They provide a valuable platform for drug discovery, target validation, and the study of gene function in disease models. Unlike other gene-editing alternatives, such as RNA interference or overexpression systems, which may have off-target effects or fail to truly mimic the complete absence of the target protein, these knockout models offer a robust approach for elucidating gene functions with high specificity and reliability.
Researchers and clinicians will find the PNRC2 Gene Knockout Cell Lines valuable due to their ability to produce reproducible experimental results, compatibility with various high-throughput screening assays, and the potential to improve understanding of gene-related mechanisms in pathophysiology. These cell lines are essential for advancing knowledge in molecular biology, thereby contributing to the development of innovative therapies.
Our company specializes in providing high-quality genetic products and cell lines, backed by extensive research expertise, ensuring that our customers receive the most reliable and effective tools for their scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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