Gene: PNPLA7
Official Full Name: patatin like domain 7, lysophospholipaseprovided by HGNC
Gene Summary: Human patatin-like phospholipases, such as PNPLA7, have been implicated in regulation of adipocyte differentiation and have been induced by metabolic stimuli (Wilson et al., 2006 [PubMed 16799181]).[supplied by OMIM, Jun 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01725 | PNPLA7 Knockout cell line (HEK293) | Human | PNPLA7 | 1:3~1:6 | Negative | Online Inquiry |
PNPLA7 Gene Knockout Cell Lines are specialized cellular models engineered to harbor a targeted disruption in the PNPLA7 gene, a member of the patatin-like phospholipase domain-containing family. This specific gene has been implicated in various metabolic processes, including lipid metabolism and energy homeostasis, making the knockout cell lines invaluable for studying its functional roles and contributions to cellular physiology.
These cell lines operate on the principle of gene editing technology, typically employing techniques such as CRISPR-Cas9 to achieve precise gene knockout. By removing the PNPLA7 gene, researchers can assess the downstream effects on metabolic pathways, observe changes in lipid profiles, and evaluate alterations in cell signaling mechanisms. This allows for in-depth exploration of conditions such as obesity, diabetes, and other metabolic disorders where PNPLA7 is suspected to play a significant role.
The scientific importance of PNPLA7 Gene Knockout Cell Lines extends into both basic research and clinical settings. They serve as critical tools for drug discovery, biomarker identification, and the development of therapeutic strategies targeting metabolic and cardiovascular diseases. As researchers strive to unravel the complexities of metabolic syndromes, these cell lines provide a controlled environment for testing hypotheses and validating potential therapeutic agents.
What sets our PNPLA7 Gene Knockout Cell Lines apart from conventional cell lines and other genetic models is their specificity and reliability. These cells are meticulously characterized to ensure high-quality performance in experimental assays, offering consistent and reproducible results. Furthermore, leveraging the latest advancements in gene editing technology guarantees that researchers are working with cutting-edge models that reflect contemporary scientific understanding.
For researchers and clinicians tackling metabolic issues, our PNPLA7 Gene Knockout Cell Lines represent a significant advancement in understanding gene function and disease mechanisms. With our commitment to high-quality biologics and a robust support system, we are equipped to empower your research efforts and facilitate breakthroughs in metabolic health. Our expertise in developing precise genetic models ensures that you receive not only a product but also a partnership in advancing scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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