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PLPP5 Knockout Cell Lines

Gene: PLPP5

Official Full Name: phospholipid phosphatase 5provided by HGNC

Gene Summary: Enables diacylglycerol diphosphate phosphatase activity and phosphatidate phosphatase activity. Involved in phospholipid dephosphorylation. Predicted to be located in cytoplasm and plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24838 PLPP5 Knockout cell line (HeLa) Human PLPP5 1:3~1:6 Negative Online Inquiry
KO24839 PLPP5 Knockout cell line (HCT 116) Human PLPP5 1:2~1:4 Negative Online Inquiry
KO24840 PLPP5 Knockout cell line (HEK293) Human PLPP5 1:3~1:6 Negative Online Inquiry
KO24841 PLPP5 Knockout cell line (A549) Human PLPP5 1:3~1:4 Negative Online Inquiry

Background

PLPP5 Gene Knockout Cell Lines are sophisticated biological tools designed to study the function of the phospholipid phosphatase enzyme, specifically phospholipid phosphatase 5 (PLPP5). These knockout cell lines are generated through targeted gene editing techniques, such as CRISPR-Cas9, to disrupt the PLPP5 gene, thereby providing a unique model system for investigating its biological roles in cellular processes.

The primary function of PLPP5 revolves around the regulation of various lipid signaling pathways, crucial for cellular homeostasis and signaling. By creating knockout cell lines, researchers can systematically examine the consequences of PLPP5 deficiency on cellular growth, apoptosis, and membrane dynamics, elucidating its involvement in disease states such as cancer or metabolic disorders. These cell lines serve as a critical platform for dissecting the molecular mechanisms underlying lipid-related cellular functions and provide insights into potential therapeutic targets.

The scientific importance of PLPP5 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They enable high-throughput screening for drug discovery, exploration of lipid metabolism pathways, and development of novel therapeutic strategies targeting lipid signaling. Additionally, the PLPP5 knockout model can help accelerate understanding of dysregulated lipid metabolism in various diseases, fostering the development of biomarkers or treatment modalities.

Unique advantages of PLPP5 Gene Knockout Cell Lines include their precision and specificity in gene editing, which allows for the elucidation of PLPP5's role without the confounding effects associated with traditional knockdown techniques. Compared to other gene editing technologies, these knockout lines offer a more stable and consistent genetic background, ensuring reproducibility in experiments.

For researchers, clinicians, and biotechnology companies, employing PLPP5 Gene Knockout Cell Lines is invaluable, as they provide a reliable and cutting-edge tool to explore complex biological questions and develop innovative solutions to pressing health issues. Our company is dedicated to delivering high-quality biological research tools, backed by extensive expertise in genetic engineering and cell line development, to support your scientific pursuits.

Please note that all services are for research use only. Not intended for any clinical use.

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