Gene: PLEKHO1
Official Full Name: pleckstrin homology domain containing O1provided by HGNC
Gene Summary: Predicted to be involved in regulation of myoblast fusion. Predicted to act upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be active in muscle cell projection membrane and ruffle membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22900 | PLEKHO1 Knockout cell line (HeLa) | Human | PLEKHO1 | 1:3~1:6 | Negative | Online Inquiry |
KO22901 | PLEKHO1 Knockout cell line (HCT 116) | Human | PLEKHO1 | 1:2~1:4 | Negative | Online Inquiry |
KO22902 | PLEKHO1 Knockout cell line (HEK293) | Human | PLEKHO1 | 1:3~1:6 | Negative | Online Inquiry |
KO22903 | PLEKHO1 Knockout cell line (A549) | Human | PLEKHO1 | 1:3~1:4 | Negative | Online Inquiry |
PLEKHO1 Gene Knockout Cell Lines are engineered cellular models specifically designed to elucidate the biological role of the PLEKHO1 gene, which has been implicated in various cellular processes including cytoskeletal dynamics and intracellular signaling pathways. This product provides researchers with an invaluable tool for dissecting the functions of PLEKHO1 in physiological and pathological contexts.
The PLEKHO1 knockout is achieved through advanced CRISPR-Cas9 technology, which allows for precise editing of the genome to abrogate the expression of the PLEKHO1 gene. This results in cellular models that lack PLEKHO1 function, enabling scientists to study the resulting phenotypic and molecular changes. Such studies are crucial for understanding the gene's contribution to diseases, particularly those involving cell migration, cancer progression, and neurodegeneration.
In a research context, these cell lines are particularly significant as they facilitate high-throughput screening for potential therapeutic targets and the investigation of gene function in disease mechanisms. Moreover, their use can streamline the development of pharmacological interventions, making them essential for both academic and clinical research settings.
What sets our PLEKHO1 Gene Knockout Cell Lines apart from conventional methods is the reliability and reproducibility of results obtained from these robust models. Unlike off-the-shelf or non-specific knockdown approaches, our cell lines provide precise elimination of the PLEKHO1 gene function with minimal off-target effects, leading to more accurate interpretations of experimental outcomes.
For researchers and clinicians alike, the PLEKHO1 Gene Knockout Cell Lines represent an essential resource that can accelerate discoveries in molecular biology and biomedical research. With a focus on quality and advanced genetic modification techniques, our company is dedicated to delivering high-performance biological products that address the evolving needs of the scientific community. We pride ourselves on providing comprehensive support for your research efforts and pioneering innovative solutions for your experimental challenges.
Please note that all services are for research use only. Not intended for any clinical use.
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