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PLEKHH1 Knockout Cell Lines

Gene: PLEKHH1

Official Full Name: pleckstrin homology, MyTH4 and FERM domain containing H1provided by HGNC

Gene Summary: Predicted to be located in cytoskeleton. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15045 PLEKHH1 Knockout cell line (HeLa) Human PLEKHH1 1:3~1:6 Negative Online Inquiry
KO15046 PLEKHH1 Knockout cell line (HCT 116) Human PLEKHH1 1:2~1:4 Negative Online Inquiry
KO15047 PLEKHH1 Knockout cell line (HEK293) Human PLEKHH1 1:3~1:6 Negative Online Inquiry
KO15048 PLEKHH1 Knockout cell line (A549) Human PLEKHH1 1:3~1:4 Negative Online Inquiry

Background

PLEKHH1 Gene Knockout Cell Lines represent a groundbreaking advancement in cellular biology research that enables scientists to investigate the functional role of the PLEKHH1 gene in various biological processes. This product comprises genetically engineered cell lines where the PLEKHH1 gene has been selectively knocked out, allowing researchers to explore the gene's contributions to cellular pathways, signaling mechanisms, and disease states without the confounding effects of its normal expression.

These knockout cell lines function as essential tools in functional genomics, serving to elucidate the pathways associated with the PLEKHH1 gene. By providing a model where the gene of interest is non-functional, scientists can assess the impact on cell growth, apoptosis, differentiation, and response to therapies. The validation of these cell lines through rigorous quality control ensures that they accurately reflect the biological outcomes of PLEKHH1 deficiency, which is critical for downstream applications, including drug discovery and development, toxicology studies, and understanding disease mechanisms.

The scientific importance of PLEKHH1 Gene Knockout Cell Lines is amplified in their application within both research and clinical settings. They facilitate studies in cancer biology, neurobiology, and metabolic disorders, where PLEKHH1 may play a pivotal role. Identifying the gene’s function can drive discoveries of novel therapeutic targets and biomarkers, contributing significantly to personalized medicine.

Compared to alternatives such as RNA interference or CRISPR/Cas9 gene editing approaches, knockout cell lines provide a stable and permanent alteration of gene expression, making them superior for long-term studies and consistent experimental results. This reproducibility is crucial for validation in scientific research and regulatory approval processes.

For researchers and clinicians alike, the availability of PLEKHH1 Gene Knockout Cell Lines embodies a valuable asset, enhancing their ability to derive insights into genetic influences on health and disease. Our company boasts extensive expertise in genetic engineering and cell line development, ensuring that our research products are designed with precision and reliability, tailored to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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