Home / PLCB1 Knockout Cell Lines

PLCB1 Knockout Cell Lines

Gene: PLCB1

Official Full Name: phospholipase C beta 1provided by HGNC

Gene Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11719 PLCB1 Knockout cell line (HeLa) Human PLCB1 1:3~1:6 Negative Online Inquiry
KO11720 PLCB1 Knockout cell line (HCT 116) Human PLCB1 1:2~1:4 Negative Online Inquiry
KO11721 PLCB1 Knockout cell line (HEK293) Human PLCB1 1:3~1:6 Negative Online Inquiry
KO11722 PLCB1 Knockout cell line (A549) Human PLCB1 1:3~1:4 Negative Online Inquiry

Background

PLCB1 Gene Knockout Cell Lines represent a groundbreaking tool in the realm of genetic research, specifically targeting the phospholipase C beta 1 (PLCB1) gene. These cell lines are genetically engineered to disable the PLCB1 gene, a crucial mediator in various signaling pathways that regulate cellular processes such as proliferation, differentiation, and apoptosis. By knocking out this gene, researchers can systematically investigate the role of PLCB1 in cellular functions and its implications in diseases, leading to deeper insights into potential therapeutic targets.

The key function of these knockout cell lines lies in their ability to provide a controlled environment for analyzing the physiological consequences of PLCB1 loss. The mechanisms involve studying altered lipid signaling pathways that affect cellular calcium levels, inositol trisphosphate (IP3) production, and downstream effects on other signaling cascades. With this detailed understanding, researchers can explore the roles of PLCB1 in cellular processes and its potential implications in conditions such as cancer, cardiovascular diseases, and neurological disorders.

From a scientific standpoint, PLCB1 Gene Knockout Cell Lines offer immense value in both academic research and clinical settings. They allow scientists to evaluate drug responses, assess the influence of cancer mutations, and develop novel treatment strategies. With the increasing focus on personalized medicine, these cell lines can play a pivotal role in tailoring therapies based on genetic predispositions.

Compared to alternative models, such as wild-type cell lines, these knockout models provide a clearer understanding of PLCB1 function. The specificity of the knockout approach reduces confounding variables, enabling more precise experimentation. They are robust tools that offer reproducible results, essential for the advancement of biomedical research.

For researchers and clinicians looking to bridge the gap between laboratory findings and clinical applications, investing in PLCB1 Gene Knockout Cell Lines is invaluable. They present a both innovative and essential resource for understanding complex signaling mechanisms and accelerating discovery in therapeutic modalities.

Our company, with extensive expertise in genetic engineering and cellular biology, strives to provide high-quality biological products that empower researchers to realize their scientific goals. By combining cutting-edge technology with a commitment to supporting the research community, we are proud to offer the PLCB1 Gene Knockout Cell Lines as a significant advancement in genetic research tools.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.