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PIP5KL1 Knockout Cell Lines

Gene: PIP5KL1

Official Full Name: phosphatidylinositol-4-phosphate 5-kinase like 1provided by HGNC

Gene Summary: PIP5KL1 is a phosphoinositide kinase-like protein that lacks intrinsic lipid kinase activity but associates with type I PIPKs (see PIP5K1A; MIM 603275) and may play a role in localization of PIPK activity (Chang et al., 2004 [PubMed 14701839]).[supplied by OMIM, Jun 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26319 PIP5KL1 Knockout cell line (HeLa) Human PIP5KL1 1:3~1:6 Negative Online Inquiry
KO26320 PIP5KL1 Knockout cell line (HCT 116) Human PIP5KL1 1:2~1:4 Negative Online Inquiry
KO26321 PIP5KL1 Knockout cell line (HEK293) Human PIP5KL1 1:3~1:6 Negative Online Inquiry
KO26322 PIP5KL1 Knockout cell line (A549) Human PIP5KL1 1:3~1:4 Negative Online Inquiry

Background

PIP5KL1 Gene Knockout Cell Lines represent a groundbreaking tool in molecular biology, designed specifically to enable the precise study of the PIP5KL1 gene's functions and its broader implications in cellular processes. These cell lines have been developed using sophisticated CRISPR/Cas9 gene-editing technology, resulting in a complete knockout of the PIP5KL1 gene, thus providing a valuable model for researchers investigating its role in phosphoinositide signaling pathways and cellular dynamics.

Key functions of the PIP5KL1 Gene Knockout Cell Lines include the ability to elucidate the biochemical pathways influenced by the absence of PIP5KL1. This gene is known to play a crucial role in regulating lipid metabolism and cellular actin dynamics, making the knockout cell lines instrumental for studying associated pathologies, including cancer progression and neurological disorders. By analyzing cellular phenotypes, researchers can uncover compensatory mechanisms and signaling cascades activated in the absence of PIP5KL1, which can lead to the identification of novel therapeutic targets.

The scientific importance of these cell lines extends to both basic research and clinical applications. They can be used to assess the efficacy of drug candidates aimed at modulating PIP5KL1-related pathways or to screen for potential biomarkers of diseases where PIP5KL1 function is altered. Additionally, these cell lines are ideal for high-throughput screening and interactions with various biological assays, which further enhances their utility in drug discovery and development.

Compared to traditional knockout models, such as conventional gene-editing approaches, the PIP5KL1 Gene Knockout Cell Lines offer superior specificity and efficiency. This precision minimizes off-target effects, ensuring that observations are directly attributable to the PIP5KL1 knockout. Furthermore, these cell lines are readily accessible and easy to culture, facilitating their incorporation into diverse experimental workflows.

For researchers and clinicians, the PIP5KL1 Gene Knockout Cell Lines provide an unparalleled opportunity to deepen understanding of lipid signaling and its implications in health and disease. The insights garnered from research utilizing these cell lines may lead to significant advancements in therapeutic strategies, markedly enhancing patient care.

Our company is committed to providing high-quality biological products that empower scientific research. With extensive expertise in gene-editing technologies and a focus on innovative solutions, we ensure that our offerings, including the PIP5KL1 Gene Knockout Cell Lines, meet the rigorous demands of cutting-edge scientific inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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