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PIP4K2B Knockout Cell Lines

Gene: PIP4K2B

Official Full Name: phosphatidylinositol-5-phosphate 4-kinase type 2 betaprovided by HGNC

Gene Summary: The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07848 PIP4K2B Knockout cell line (HeLa) Human PIP4K2B 1:3~1:6 Negative Online Inquiry
KO07849 PIP4K2B Knockout cell line (HCT 116) Human PIP4K2B 1:2~1:4 Negative Online Inquiry
KO07850 PIP4K2B Knockout cell line (HEK293) Human PIP4K2B 1:3~1:6 Negative Online Inquiry
KO07851 PIP4K2B Knockout cell line (A549) Human PIP4K2B 1:3~1:4 Negative Online Inquiry

Background

PIP4K2B Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the phosphatidylinositol phosphate kinase 2 beta (PIP4K2B) gene and its associated signaling pathways. By utilizing CRISPR-Cas9 technology to create precise genetic modifications, these cell lines effectively eliminate PIP4K2B expression, allowing researchers to explore the gene's role in various biological processes and disease states. The knockout mechanism enhances the understanding of both the contributory pathways influenced by PIP4K2B and the downstream effects resulting from its absence.

These knockout cell lines serve as powerful tools in cellular and molecular biology research, providing insights into the gene’s implications in cell growth, apoptosis, and metabolism. The scientific importance of PIP4K2B extends to its involvement in cancer biology, neurodegenerative diseases, and metabolic syndromes, highlighting its potential as a therapeutic target. Researchers can leverage these models to investigate signaling network alterations and evaluate new drugs aimed at modulating these pathways in preclinical studies.

What sets PIP4K2B Gene Knockout Cell Lines apart from alternative models is their enhanced specificity and reliability. The use of CRISPR-Cas9 ensures precise gene editing, eliminating off-target effects common in other knockout methods. Additionally, the availability of various cellular backgrounds allows customization in experimental design, catering to specific research needs.

For researchers and clinicians, PIP4K2B Gene Knockout Cell Lines represent invaluable resources that streamline the investigative process, reduce time-to-discovery, and promote translational research outcomes. The expertise of our company in molecular genetics ensures that our cell lines are rigorously validated and provide consistent performance, enabling reliable results for your research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

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