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PHF20 Knockout Cell Lines

Gene: PHF20

Official Full Name: PHD finger protein 20provided by HGNC

Gene Summary: Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol; nuclear membrane; and nucleoplasm. Part of MLL1 complex and NSL complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00423 PHF20 Knockout cell line (HEK293) Human PHF20 1:3~1:6 Negative Online Inquiry
KO22837 PHF20 Knockout cell line (HeLa) Human PHF20 1:3~1:6 Negative Online Inquiry
KO22838 PHF20 Knockout cell line (HCT 116) Human PHF20 1:2~1:4 Negative Online Inquiry
KO22839 PHF20 Knockout cell line (A549) Human PHF20 1:3~1:4 Negative Online Inquiry

Background

PHF20 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene editing to disrupt the expression of the PHF20 gene. This innovative product plays a crucial role in the study of gene function, cellular processes, and disease mechanisms. By providing a model system devoid of PHF20 expression, researchers can elucidate the specific roles this gene plays in various biological pathways, including those associated with cancer progression and stem cell biology.

Key functions of PHF20 gene knockout cell lines arise from their utility in various experimental settings. The lack of PHF20 allows scientists to investigate pathways normally modulated by this gene, enabling the analysis of downstream signaling effects and compensatory mechanisms that may occur in vivo. The use of these cell lines facilitates improved understanding of gene interactions and offers a platform for testing potential therapeutic approaches targeting related pathways.

The scientific importance of PHF20 knockout models is underscored by their applications in both research and clinical settings. These cell lines provide a valuable resource for studying tumor biology, drug responses, and genetic diseases. Their use in high-throughput screening and functional genomics studies expands the horizons of molecular research, positioning them as essential tools in the areas of cancer therapy development and regenerative medicine.

What sets PHF20 gene knockout cell lines apart from alternative models is their precision and specificity. Utilizing advanced CRISPR/Cas9 technology ensures a clean gene-editing process, resulting in consistent knockout efficiency and highly reliable experimental outcomes. Furthermore, their compatibility with a variety of cellular assays, including proliferation, migration, and invasion studies, marks them as versatile tools for biological research.

For researchers and clinicians focused on understanding complex biological systems and translating findings into clinical applications, the PHF20 Gene Knockout Cell Lines represent an invaluable addition to their toolkit. By enabling targeted research that can lead to novel therapeutic strategies, these products are essential in the pursuit of advancements in biomedical sciences.

Our company prides itself on developing cutting-edge biological tools backed by rigorous scientific research and expertise. We remain committed to providing high-quality resources that empower the scientific community in their quest for innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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