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PGGHG Knockout Cell Lines

Gene: PGGHG

Official Full Name: protein-glucosylgalactosylhydroxylysine glucosidaseprovided by HGNC

Gene Summary: Enables protein-glucosylgalactosylhydroxylysine glucosidase activity. Involved in carbohydrate metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26182 PGGHG Knockout cell line (HeLa) Human PGGHG 1:3~1:6 Negative Online Inquiry
KO26183 PGGHG Knockout cell line (HCT 116) Human PGGHG 1:2~1:4 Negative Online Inquiry
KO26184 PGGHG Knockout cell line (HEK293) Human PGGHG 1:3~1:6 Negative Online Inquiry
KO26185 PGGHG Knockout cell line (A549) Human PGGHG 1:3~1:4 Negative Online Inquiry

Background

PGGHG Gene Knockout Cell Lines are sophisticated biological tools engineered to enable the precise study of gene function and the underlying mechanisms of disease. These cell lines have been generated using state-of-the-art CRISPR/Cas9 technology, allowing for the targeted ablation of the PGGHG gene, which is critically involved in various metabolic pathways. The manipulation of gene expression in these cell lines offers researchers an unparalleled opportunity to dissect the roles of PGGHG in cellular processes and its contributions to pathophysiological conditions.

Mechanistically, PGGHG Gene Knockout Cell Lines operate by disabling the gene of interest, leading to the loss of its encoded protein, which in turn affects downstream signaling pathways and metabolic functions. This creates a cellular model that mimics genetic disorders or responses to treatment, facilitating in-depth analyses of gene function, drug interaction, and the molecular basis of diseases. Such models are invaluable across a range of applications from basic research to drug discovery and development, allowing for the identification of novel therapeutic targets.

The scientific importance of these cell lines lies not only in their versatility for experimental setups but also their unique ability to highlight the effects of specific gene loss in a controlled environment. Unlike traditional cell lines that may express variable levels of the target gene, PGGHG Gene Knockout Cell Lines provide consistent and reproducible results, thus increasing the reliability of experimental outcomes.

Researchers and clinicians will appreciate the advantages these cell lines offer, including their ease of use, adaptability for high-throughput screening, and compatibility with various assays. Moreover, the specificity and precision of gene knockout enhance the clarity of results, which is pivotal for hypothesis-driven research.

In conclusion, PGGHG Gene Knockout Cell Lines represent a cutting-edge solution for advancing genetic research and therapeutic interventions. Our company stands at the forefront of biotechnological advancements, committed to providing high-quality, reliable products that empower scientific discovery and innovation. We are dedicated to supporting researchers and clinicians in their quest to unlock critical biological insights and translate discoveries into impactful treatments.

Please note that all services are for research use only. Not intended for any clinical use.

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