Gene: PDLIM4
Official Full Name: PDZ and LIM domain 4provided by HGNC
Gene Summary: Enables alpha-actinin binding activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in actin cytoskeleton organization. Located in several cellular components, including lamellipodium; perinuclear region of cytoplasm; and stress fiber. Part of filamentous actin. Implicated in osteoporosis. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34038 | PDLIM4 Knockout cell line (HEK293) | Human | PDLIM4 | 1:3~1:6 | Negative | Online Inquiry |
PDLIM4 Gene Knockout Cell Lines are specialized cellular models designed to study the functions of the PDLIM4 gene through the complete removal of its coding sequence, allowing researchers to explore the consequences of its absence in a controlled environment. This innovative tool is pivotal for understanding the biological roles that PDLIM4 plays in cellular processes, including cell growth, differentiation, and response to external stressors. The knockout mechanism relies on advanced CRISPR-Cas9 technology, which enables precise gene editing and facilitates high specificity while minimizing off-target effects.
In research and clinical settings, PDLIM4 Gene Knockout Cell Lines are instrumental in elucidating the gene's involvement in various pathological conditions, particularly its implications in cancer biology and immune response. By providing a means to investigate the phenotypic and molecular alterations resulting from PDLIM4 gene deletion, these cell lines serve as invaluable resources for drug discovery and the development of targeted therapies.
Compared to traditional cell lines that may express varying levels of the PDLIM4 gene, these knockout models offer researchers a consistent and reliable system to study the specific impacts of PDLIM4 loss. This feature enhances reproducibility and allows for more straightforward interpretations of experimental outcomes. Moreover, the use of gene knockout technology places these cell lines at the forefront of modern genetic research, offering unique insights that are increasingly relevant in translational science.
For researchers and clinicians adept at navigating the complexities of gene function and disease mechanisms, PDLIM4 Gene Knockout Cell Lines present an unparalleled opportunity to advance knowledge and therapeutic strategies. Our company prides itself on delivering high-quality biological products backed by robust research and development expertise, ensuring that each product meets the rigorous standards required for cutting-edge studies.
Please note that all services are for research use only. Not intended for any clinical use.
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