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PDCD10 Knockout Cell Lines

Gene: PDCD10

Official Full Name: programmed cell death 10provided by HGNC

Gene Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00511 PDCD10 Knockout cell line (HEK293) Human PDCD10 1:3~1:6 Negative Online Inquiry
KO05853 PDCD10 Knockout cell line (HeLa) Human PDCD10 1:3~1:6 Negative Online Inquiry
KO05854 PDCD10 Knockout cell line (HCT 116) Human PDCD10 1:2~1:4 Negative Online Inquiry
KO05855 PDCD10 Knockout cell line (A549) Human PDCD10 1:3~1:4 Negative Online Inquiry

Background

PDCD10 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to facilitate the study of programmed cell death 10 (PDCD10), a protein implicated in various cellular processes, including apoptosis and cell proliferation. By knocking out the PDCD10 gene, these cell lines provide researchers with a powerful tool for dissecting the functional roles of this protein, particularly in the context of cancer, cardiovascular diseases, and neurodegenerative disorders.

The key function of PDCD10 Gene Knockout Cell Lines lies in their ability to mimic the loss of PDCD10 expression, allowing for the investigation of the downstream effects on cellular signaling pathways and phenotypic outcomes. Researchers can utilize these cell lines to explore cellular behaviors, such as alterations in apoptosis, angiogenesis, and inflammatory responses, thereby elucidating the molecular mechanisms by which PDCD10 may contribute to disease pathology.

The scientific importance of PDCD10 Gene Knockout Cell Lines is underscored by their applications in both basic and translational research settings. These cell lines enable the evaluation of potential drug targets and therapeutic strategies related to PDCD10 dysfunction, paving the way for advancements in precision medicine approaches. Specifically, the ability to conduct high-throughput screenings for drug efficacy and to analyze gene interactions in a controlled environment marks their contribution to unlocking new avenues in biological research.

What sets PDCD10 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility in gene knockout efficiency. Built on cutting-edge CRISPR/Cas9 gene-editing technology, our cell lines ensure comprehensive loss-of-function studies while providing a reliable platform for downstream applications, such as gene expression analysis and proteomics. Additionally, they come fully validated and characterized for consistency, thus saving valuable time and resources for researchers.

These cell lines are invaluable tools for researchers and clinicians aiming to deepen their understanding of PDCD10's role in health and disease. Their deployment not only aids in advancing fundamental biological knowledge but also enhances the potential for developing novel therapeutic interventions.

As a company dedicated to providing high-quality biological products, we leverage extensive expertise in genetic engineering and cell culture technologies. Our commitment to scientific rigor and customer satisfaction ensures that our PDCD10 Gene Knockout Cell Lines meet the highest standards for research excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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