Gene: PCSK1N
Official Full Name: proprotein convertase subtilisin/kexin type 1 inhibitorprovided by HGNC
Gene Summary: The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27628 | PCSK1N Knockout cell line (HEK293) | Human | PCSK1N | 1:3~1:6 | Negative | Online Inquiry |
KO27629 | PCSK1N Knockout cell line (A549) | Human | PCSK1N | 1:3~1:4 | Negative | Online Inquiry |
PCSK1N Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology and genetics, specifically targeting the proprotein convertase subtilisin/kexin type 1 inhibitor (PCSK1N) gene. These engineered cell lines have been meticulously developed to knock out the PCSK1N gene, thereby enabling researchers to study its biological functions and interactions more comprehensively. The knockout of this gene leads to the loss of its protein product, which is known to play a critical role in neuroendocrine processes, given its involvement in hormone processing.
The primary mechanism of action of these knockout cell lines involves the ablation of PCSK1N's regulatory functions, providing a clear view of its role in various physiological processes. By utilizing CRISPR-Cas9 technology, the knockout model allows for precise genomic editing, facilitating experimental designs that explore the implications of PCSK1N deficiency in metabolic pathways, neuroendocrine signaling, and pathophysiological conditions such as obesity, diabetes, and neurodegenerative diseases.
The scientific importance of PCSK1N Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings. Researchers can leverage these cell lines to investigate the molecular underpinnings of various diseases, validate therapeutic targets, and screen potential drug compounds. Moreover, their use can refine our understanding of the consequences of PCSK1N loss, thereby offering insights valuable for developing innovative therapies.
Unlike traditional cell lines that may retain wild-type characteristics, these knockout cell lines offer a unique advantage by providing a solely PCSK1N-deficient background, ensuring results are specific and accurate. The ability to generate a consistent and reproducible model makes these cell lines indispensable for hypothesis-driven experiments, particularly in studies involving endocrine regulation.
For researchers, clinicians, and pharmaceutical companies focused on metabolic and endocrine disorders, adopting PCSK1N Gene Knockout Cell Lines can markedly enhance experimental outcomes and accelerate the discovery of impactful clinical solutions. Our company has extensive expertise in genetic engineering and cellular biology, ensuring that our products not only meet but exceed the expectations of the scientific community, empowering researchers to navigate the complexities of gene function with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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