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PCMTD2 Knockout Cell Lines

Gene: PCMTD2

Official Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2provided by HGNC

Gene Summary: Predicted to enable protein-L-isoaspartate (D-aspartate) O-methyltransferase activity. Predicted to be involved in protein modification process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15292 PCMTD2 Knockout cell line (HeLa) Human PCMTD2 1:3~1:6 Negative Online Inquiry
KO15293 PCMTD2 Knockout cell line (HCT 116) Human PCMTD2 1:2~1:4 Negative Online Inquiry
KO15294 PCMTD2 Knockout cell line (HEK293) Human PCMTD2 1:3~1:6 Negative Online Inquiry
KO15295 PCMTD2 Knockout cell line (A549) Human PCMTD2 1:3~1:4 Negative Online Inquiry

Background

PCMTD2 Gene Knockout Cell Lines are essential tools for studying the biological functions of the PCMTD2 gene, which encodes the protein known as protein-L-isoaspartate O-methyltransferase domain-containing protein 2. This product entails engineered cell lines where the PCMTD2 gene has been specifically disrupted, facilitating researchers in elucidating the gene's roles in cellular pathways and disease mechanisms.

The core function of the PCMTD2 Gene Knockout Cell Lines lies in their ability to model the absence of PCMTD2 protein, allowing scientists to observe resultant phenotypic changes and explore downstream effects that influence cell signaling, apoptosis, and metabolic functions. By utilizing CRISPR/Cas9 or similar gene-editing technologies, the knockout ensures a precise manipulation at the genomic level, leading to reliable and reproducible results in subsequent assays.

The scientific importance of these cell lines extends into various research fields, including cancer biology, neurodegenerative disorders, and regenerative medicine. They serve as invaluable models to study differential gene expression, protein interactions, and the cellular response to environmental stimuli, offering insights that are pivotal for advancing therapeutic strategies.

Compared to alternative gene manipulation techniques or platforms, the PCMTD2 Gene Knockout Cell Lines provide unique advantages, including a stable genomic alteration that enables long-term studies, straightforward experimental design, and compatibility with high-throughput screening applications. These attributes ensure that researchers can gather robust data while minimizing variability.

For researchers and clinicians, the ability to directly investigate the functions of PCMTD2 can inform future studies focused on therapeutic interventions and biological mechanisms underlying disease states. The accessibility of these cell lines allows for an efficient exploration of hypotheses relating to protein function and interaction.

As a leader in the production of high-quality biological research tools, our company is committed to empowering scientific inquiry with state-of-the-art products. We prioritize rigorous quality control and customer support, ensuring that your research efforts yield meaningful and impactful results.

Please note that all services are for research use only. Not intended for any clinical use.

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