Gene: PCDH9
Official Full Name: protocadherin 9provided by HGNC
Gene Summary: This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may be involved in signaling at neuronal synaptic junctions. Sharing a characteristic with other protocadherin genes, this gene has a notably large exon that encodes multiple cadherin domains and a transmembrane region. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36195 | PCDH9 Knockout cell line (HEK293) | Human | PCDH9 | 1:3~1:6 | Negative | Online Inquiry |
KO36196 | PCDH9 Knockout cell line (A549) | Human | PCDH9 | 1:3~1:4 | Negative | Online Inquiry |
PCDH9 Gene Knockout Cell Lines are specialized biological products designed for the study of gene function and the molecular mechanisms underlying various diseases. These cell lines are developed using advanced CRISPR-Cas9 technology to precisely disrupt the PCDH9 gene, which encodes for a member of the protocadherin family involved in cellular adhesion and signaling pathways. By knocking out this gene, researchers can investigate its role in processes such as neural development, synaptic plasticity, and potential implications in psychiatric disorders.
The primary function of PCDH9 Gene Knockout Cell Lines lies in their ability to provide insights into the functional consequences of PCDH9 loss. Researchers can utilize these cell lines to assess changes in cellular behavior, gene expression patterns, and interactions with other cellular components in a controlled environment. The knockout model facilitates the elucidation of signaling pathways affected by the absence of PCDH9, making it an essential tool for both basic research and therapeutic development.
Scientific studies have highlighted the importance of PCDH9 in neurobiology, as aberrations in this gene have been associated with various neurological conditions. Consequently, these cell lines are invaluable for exploring potential targets for therapeutics and understanding the etiology of related disorders. Compared to traditional gene knockdown approaches, CRISPR-based knockout strategies offer higher specificity and efficiency, minimizing off-target effects and providing robust models for investigation.
The unique selling points of PCDH9 Gene Knockout Cell Lines include their high fidelity in genetic alteration and the availability of inner control mechanisms that streamline validation processes. These cell lines are designed for ease of use, enabling researchers and clinicians to rapidly implement experiments without extensive preliminary optimization. This translates to time and resource savings, enhancing the overall throughput of research projects.
For researchers, clinicians, and biopharmaceutical companies focused on genetic research and therapeutic innovations, PCDH9 Gene Knockout Cell Lines present an indispensable resource for advancing knowledge and developing novel interventions. Our company prides itself on being at the forefront of gene editing technology, providing a diverse range of validated cell lines and custom solutions to meet the needs of the scientific community, reinforcing our commitment to enabling breakthroughs in biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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