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PARM1 Knockout Cell Lines

Gene: PARM1

Official Full Name: prostate androgen-regulated mucin-like protein 1provided by HGNC

Gene Summary: Located in several cellular components, including Golgi apparatus; endosome; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28729 PARM1 Knockout cell line (HCT 116) Human PARM1 1:2~1:4 Negative Online Inquiry
KO28730 PARM1 Knockout cell line (HEK293) Human PARM1 1:3~1:6 Negative Online Inquiry
KO28731 PARM1 Knockout cell line (A549) Human PARM1 1:3~1:4 Negative Online Inquiry

Background

The PARM1 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the functional study of the PARM1 gene by enabling the analysis of its biological roles through gene disruption. Utilizing state-of-the-art CRISPR-Cas9 gene-editing technology, this product allows researchers to create precise deletions in the PARM1 gene, leading to a complete lack of expression of this gene product.

The primary mechanism of the PARM1 Gene Knockout Cell Lines hinges on the targeted alteration of genetic material, which results in lossof-function mutations that researchers can leverage to dissect pathways in which PARM1 is implicated. This functionality is paramount in understanding various cellular mechanisms, particularly those involved in cell signaling, growth regulation, and oncogenesis.

The significance of these cell lines extends to multiple research applications, including cancer biology, developmental biology, and cellular physiology. In clinical settings, understanding PARM1's role can illuminate disease mechanisms and potentially identify novel therapeutic targets, making these knockout cell lines a crucial resource for translational research.

What sets the PARM1 Gene Knockout Cell Lines apart from alternative products is their high specificity and efficiency in gene modification, coupled with the ability to generate stable, homogeneous cell populations that can be utilized in various downstream assays, such as high-throughput screening or gene expression analysis. Researchers benefit from seamless integration into existing workflows, ultimately enhancing experimental reproducibility and reliability.

By equipping researchers and clinicians with a sophisticated tool for gene editing, the PARM1 Gene Knockout Cell Lines provide a vital edge in advancing our understanding of gene function and disease pathology. Our company has a strong commitment to delivering cutting-edge biological tools, backed by rigorous validation and support, ensuring that scientists can focus on discovering insights that shape the future of medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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