Gene: PACS2
Official Full Name: phosphofurin acidic cluster sorting protein 2provided by HGNC
Gene Summary: Predicted to enable transmembrane transporter binding activity. Involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Acts upstream of or within protein localization to phagophore assembly site. Located in endoplasmic reticulum and mitochondrion. Implicated in developmental and epileptic encephalopathy 66. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29634 | PACS2 Knockout cell line (HeLa) | Human | PACS2 | 1:3~1:6 | Negative | Online Inquiry |
KO29635 | PACS2 Knockout cell line (HCT 116) | Human | PACS2 | 1:2~1:4 | Negative | Online Inquiry |
KO29636 | PACS2 Knockout cell line (HEK293) | Human | PACS2 | 1:3~1:6 | Negative | Online Inquiry |
KO29637 | PACS2 Knockout cell line (A549) | Human | PACS2 | 1:3~1:4 | Negative | Online Inquiry |
PACS2 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the rigorous study of the PACS2 gene, a key player in intracellular transport and protein sorting. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide researchers with a powerful tool to explore the functional implications of PACS2 depletion on cellular processes.
The primary mechanism by which PACS2 Gene Knockout Cell Lines operate involves the complete ablation of PACS2 gene expression, resulting in an altered cellular environment that mimics conditions of PACS2 deficiency. This creates a unique opportunity for scientists to investigate cellular pathways associated with trafficking, signaling, and apoptosis, as well as to examine the potential implications of PACS2 loss in disease states, particularly in neurodegenerative disorders and cancer.
In clinical settings and research environments, these cell lines serve as invaluable systems for drug screening, biomarker discovery, and the elucidation of molecular mechanisms underlying PACS2-related functions. Their application extends beyond basic science, providing insights that may guide therapeutic interventions and contribute to the development of targeted treatments.
One of the significant advantages of PACS2 Gene Knockout Cell Lines is their specificity and reliability; unlike traditional methods that may yield varying results, these knockout lines ensure consistent and reproducible data. This precision is crucial in understanding the multifaceted roles of PACS2 in various biological contexts, making them preferable over alternative models.
Researchers and clinicians can derive great value from utilizing these cell lines due to their potential to unlock new avenues for understanding cellular dynamics and disease mechanisms. By enabling targeted experiments, they can accelerate research timelines and improve the quality of insights gained.
At [Your Company Name], we pride ourselves on our expertise in creating high-quality biological products tailored for cutting-edge research. Our PACS2 Gene Knockout Cell Lines stand as a testament to our commitment to advancing scientific discovery and supporting the research community with exceptional tools that inspire innovation and progress.
Please note that all services are for research use only. Not intended for any clinical use.
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