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PABIR2 Knockout Cell Lines

Gene: PABIR2

Official Full Name: PABIR family member 2provided by HGNC

Gene Summary: Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15398 PABIR2 Knockout cell line (HeLa) Human PABIR2 1:3~1:6 Negative Online Inquiry
KO15399 PABIR2 Knockout cell line (HCT 116) Human PABIR2 1:2~1:4 Negative Online Inquiry
KO15400 PABIR2 Knockout cell line (HEK293) Human PABIR2 1:3~1:6 Negative Online Inquiry
KO15401 PABIR2 Knockout cell line (A549) Human PABIR2 1:3~1:4 Negative Online Inquiry

Background

PABIR2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the PABIR2 gene's function and its implications in cellular processes. By employing the CRISPR-Cas9 genome-editing technology, these cell lines enable precise disruption of the PABIR2 gene, allowing researchers to analyze the resulting phenotypic changes and molecular interactions within various biological pathways. The invalidation of PABIR2 not only elucidates its role in cellular events such as proliferation, differentiation, and apoptosis but also offers insights into its potential involvement in disease mechanisms, particularly in cancer biology and other disorders.

The primary mechanism by which PABIR2 Gene Knockout Cell Lines operate involves the introduction of double-strand breaks in the DNA at specific loci, leading to errors during the repair process that ultimately result in the knockout of the target gene. This targeted approach ensures high specificity and efficiency, reducing off-target effects commonly encountered in traditional gene editing techniques.

From a scientific perspective, these cell lines are invaluable tools in both research and clinical contexts. They enable the investigation of gene function at a molecular level and provide a model for testing therapeutic interventions aimed at diseases linked to PABIR2 dysregulation. Researchers can use these tools to explore gene expression profiles, signaling pathways, and potential biomarkers for disease progression.

One key advantage of the PABIR2 Gene Knockout Cell Lines compared to alternative approaches is their enhanced specificity and reliability. Many existing models lack the precision required for thorough investigation, while these engineered lines offer a straightforward method for generating unambiguous data on gene function and its biological implications.

For researchers, clinicians, and pharmaceutical developers, the PABIR2 Gene Knockout Cell Lines represent a critical resource. They empower users to probe the complexities of gene function and therapeutic candidates, facilitating the advancement of knowledge in genomic research and paving the way for novel treatments.

Lastly, our company is committed to advancing biological research and clinical applications by providing high-quality genetic tools, exemplified by our PABIR2 Gene Knockout Cell Lines, developed with rigorous quality control and expert scientific input to support the needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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