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PABIR1 Knockout Cell Lines

Gene: PABIR1

Official Full Name: PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1provided by HGNC

Gene Summary: Enables protein phosphatase 2A binding activity and protein serine/threonine phosphatase inhibitor activity. Involved in mitotic G2/M transition checkpoint; positive regulation of cell growth; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15402 PABIR1 Knockout cell line (HeLa) Human PABIR1 1:3~1:6 Negative Online Inquiry
KO15403 PABIR1 Knockout cell line (HCT 116) Human PABIR1 1:2~1:4 Negative Online Inquiry
KO15404 PABIR1 Knockout cell line (HEK293) Human PABIR1 1:3~1:6 Negative Online Inquiry
KO15405 PABIR1 Knockout cell line (A549) Human PABIR1 1:3~1:4 Negative Online Inquiry

Background

PABIR1 Gene Knockout Cell Lines are sophisticated biological tools designed for the study of the PABIR1 gene's function and its implications in various cellular processes. Utilizing CRISPR-Cas9 genome editing technology, these cell lines are generated to create precise deletions in the PABIR1 gene, allowing researchers to investigate the phenotypic consequences of its absence. This targeted disruption is vital for understanding the gene's role in pathways related to RNA binding, cellular stress response, and potential implications in oncogenesis.

The key mechanism that underpins the functionality of PABIR1 Gene Knockout Cell Lines involves the generation of null mutations in the coding sequence of the PABIR1 gene. The resulting cell lines exhibit traits reflective of altered gene expression, enabling comprehensive analysis of downstream effects. Researchers can utilize these cell lines to explore various biological questions, including gene regulation, protein interaction networks, and cellular respiration dynamics, thereby contributing to broader research themes in cancer biology and genetic disorders.

In clinical and research settings, PABIR1 Gene Knockout Cell Lines are invaluable for drug discovery and the development of targeted therapies. Their ability to mimic certain pathological conditions makes them an excellent model for evaluating therapeutic interventions aimed at modulating PABIR1 activity. Unlike conventional cell lines, our knockout models provide a more accurate representation of genetic alterations present in disease, leading to more reliable data and insights.

One unique selling point of our PABIR1 Gene Knockout Cell Lines is the rigorous quality assurance we implement during their development. Our lines are verified through deep sequencing to confirm gene disruption, ensuring that researchers receive genuine products that facilitate successful experimentation. Enhanced reproducibility and a clear molecular profile set our cell lines apart from competitors, providing reassurance to users concerned with research integrity.

By investing in PABIR1 Gene Knockout Cell Lines, researchers and clinicians are equipped with powerful tools that can expedite their scientific inquiries and bring translational insights to the forefront. Our commitment to excellence in developing biological products makes us a leader in the field, ensuring that you have access to innovative solutions that drive discovery and advance knowledge within biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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