Gene: Otub1
Official Full Name: OTU deubiquitinase, ubiquitin aldehyde binding 1provided by RGD
Gene Summary: Predicted to enable several functions, including ubiquitin protein ligase binding activity; ubiquitin-like protein peptidase activity; and ubiquitin-protein transferase inhibitor activity. Involved in cellular response to interleukin-1. Predicted to be located in cytoplasm and membrane. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01268 | Otub1 Knockout cell line (H9c2(2-1)) | Rat | Otub1 | Negative | Online Inquiry |
Otub1 Gene Knockout Cell Lines are genetically engineered cell lines in which the Otub1 gene, known for its role in deubiquitination processes, has been selectively inactivated. This innovative tool provides researchers a unique opportunity to study the functional implications of Otub1 deficiency in various biological contexts, particularly in cellular pathways involving protein degradation and signal transduction.
The primary function of the Otub1 gene is to encode a deubiquitinating enzyme that removes ubiquitin moieties from proteins, thereby regulating their stability and activity. Knockout of this gene can lead to altered cellular responses to stress, changes in protein turnover, and dysregulation of critical signaling pathways, making these cell lines invaluable for investigating mechanisms of pathophysiology, especially in cancer and neurodegenerative diseases.
Scientifically, Otub1 Gene Knockout Cell Lines hold significant importance in both basic and applied research settings. They serve as robust models for elucidating the role of deubiquitination in disease models, drug response, and cellular homeostasis. Clinically, insights gained from these models may inform the development of targeted therapies, ultimately enhancing patient outcomes.
What sets our Otub1 Gene Knockout Cell Lines apart from alternative models is the precision of our genetic engineering techniques, ensuring high specificity and reproducibility. These cell lines undergo rigorous quality control measures to provide consistent performance metrics for investigative studies. Furthermore, our cells are derived from various tissue types, allowing for a diverse array of experimental applications.
For researchers and clinicians, these cell lines offer an essential tool for advancing understanding of molecular mechanisms governing cellular behavior. By leveraging our Otub1 Gene Knockout Cell Lines, users can gain access to an unparalleled resource aimed at uncovering novel therapeutic strategies.
Our company specializes in advanced biological products, and we pride ourselves on providing high-quality, innovative research tools designed to support the scientific community in answering complex biological questions. We are committed to excellence in genetic engineering and consumer support, ensuring that researchers have the best resources available for their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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