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OVGP1 Knockout Cell Lines

Gene: OVGP1

Official Full Name: oviductal glycoprotein 1provided by HGNC

Gene Summary: This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36254 OVGP1 Knockout cell line (HCT 116) Human OVGP1 1:2~1:4 Negative Online Inquiry
KO36255 OVGP1 Knockout cell line (HEK293) Human OVGP1 1:3~1:6 Negative Online Inquiry
KO36256 OVGP1 Knockout cell line (A549) Human OVGP1 1:3~1:4 Negative Online Inquiry

Background

OVGP1 Gene Knockout Cell Lines are genetically modified cell lines in which the OVGP1 gene has been deliberately disrupted, enabling researchers to study the biological functions and clinical implications of OVGP1 more effectively. OVGP1, or Oviductal Glycoprotein 1, is a significant protein involved in reproductive biology, particularly in the fertilization process and early embryonic development. The knockout of this gene allows researchers to identify its precise roles and the mechanisms by which it influences reproductive outcomes.

The key function of these knockout cell lines lies in their ability to reveal OVGP1's involvement in various cellular processes, such as cellular adhesion, protein glycosylation, and interactions with sperm and the oviduct. By utilizing these models, scientists can investigate the downstream effects of OVGP1 loss on reproductive health, including infertility and developmental disorders, thereby uncovering potential therapeutic targets.

From a scientific perspective, OVGP1 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They provide a robust tool for drug discovery and can facilitate the understanding of reproductive disorders. Their specific applications are crucial in elucidating the underlying mechanisms of diseases related to reproductive health.

What sets OVGP1 Gene Knockout Cell Lines apart from other genetic models is their specificity and relevance to human reproduction, allowing for more translatable findings. In comparison to traditional cell lines, these knockout models offer a unique approach to dissect biological pathways with accuracy and precision.

For researchers and clinicians focused on reproductive biology, the use of the OVGP1 Gene Knockout Cell Lines can significantly enhance the validity of experimental outcomes, leading to breakthroughs in understanding infertility and related health issues. Our company is dedicated to advancing biological research through high-quality, tailored genetic products, ensuring that researchers have the tools necessary to push the boundaries of scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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