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OSBPL9 Knockout Cell Lines

Gene: OSBPL9

Official Full Name: oxysterol binding protein like 9provided by HGNC

Gene Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30703 OSBPL9 Knockout cell line (HeLa) Human OSBPL9 1:3~1:6 Negative Online Inquiry
KO30704 OSBPL9 Knockout cell line (HCT 116) Human OSBPL9 1:2~1:4 Negative Online Inquiry
KO30705 OSBPL9 Knockout cell line (HEK293) Human OSBPL9 1:3~1:6 Negative Online Inquiry
KO30706 OSBPL9 Knockout cell line (A549) Human OSBPL9 1:3~1:4 Negative Online Inquiry

Background

OSBPL9 Gene Knockout Cell Lines are specialized cellular models in which the OSBPL9 gene, known to play a critical role in lipid metabolism and intracellular signaling, has been selectively disrupted through advanced CRISPR-Cas9 gene editing techniques. This sophisticated manipulation enables researchers to gain profound insights into the biological functions and regulatory mechanisms of OSBPL9, thus facilitating the study of its involvement in various cellular processes including lipid homeostasis, cell proliferation, and apoptosis.

The knockout of the OSBPL9 gene effectively removes the gene's expression, leading to downstream effects that can elucidate its role in pathology, particularly in conditions such as metabolic disorders and certain cancers. These cell lines serve as invaluable tools for investigating the gene's function and impact on cellular physiology in controlled experimental settings. By providing a model that mimics specific biological environments, researchers can better explore therapeutic targets and assess the efficacy of novel compounds aimed at modulating the pathways associated with OSBPL9.

One of the primary advantages of our OSBPL9 Gene Knockout Cell Lines lies in their high specificity and reproducibility. Unlike other genetic modification methods, CRISPR-Cas9 offers precise gene editing capabilities with minimal off-target effects, ultimately enhancing experimental accuracy. Furthermore, these cell lines can be utilized in various high-throughput screening applications, making them essential for both academic research and clinical drug discovery.

For researchers and clinicians, the OSBPL9 Gene Knockout Cell Lines represent a unique opportunity to contribute to the understanding of lipid-related diseases and uncover potential new treatments. Our company's expertise in creating high-quality, validated cell lines ensures that users receive a reliable and effective tool conducive to their research objectives. By choosing our OSBPL9 Gene Knockout Cell Lines, you are equipping yourself with a cutting-edge resource that stands to advance both scientific inquiry and clinical advancements in a meaningful way.

Please note that all services are for research use only. Not intended for any clinical use.

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