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OR8U8 Knockout Cell Lines

Gene: OR8U8

Official Full Name: olfactory receptor family 8 subfamily U member 8provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15476 OR8U8 Knockout cell line (HeLa) Human OR8U8 1:3~1:6 Negative Online Inquiry
KO15477 OR8U8 Knockout cell line (HCT 116) Human OR8U8 1:2~1:4 Negative Online Inquiry
KO15478 OR8U8 Knockout cell line (HEK293) Human OR8U8 1:3~1:6 Negative Online Inquiry
KO15479 OR8U8 Knockout cell line (A549) Human OR8U8 1:3~1:4 Negative Online Inquiry

Background

OR8U8 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to aid in the investigation of olfactory receptor gene functions. These cell lines have undergone precise genome editing techniques, such as CRISPR-Cas9, to effectively knock out the OR8U8 gene, resulting in the ablation of its normal expression and permitting comprehensive studies of the gene's role in olfactory signaling and physiological processes.

The primary function of the OR8U8 Gene Knockout Cell Lines is to facilitate the exploration of olfactory receptor pathways, allowing researchers to isolate and analyze how the absence of OR8U8 influences cellular behavior, receptor signaling, and downstream effects, including neural response mechanisms. This insight is crucial for understanding the complexities of sensory perception and could lead to advancements in treating olfactory dysfunctions or related neurological disorders.

The scientific importance of these cell lines extends to both research and clinical applications. They offer an invaluable tool for pharmaceutical and biotech sectors aiming to develop novel therapeutics targeting olfactory pathways or for academic researchers investigating the genetic basis of olfactory-related behaviors. The ability to examine the specific involvement of OR8U8 provides a direct avenue for elucidating broader olfactory signaling cascades and their implications for human health.

Unique advantages of the OR8U8 Gene Knockout Cell Lines include their specificity, ease of use, and reproducibility compared to alternative models. Unlike traditional approaches that may rely on overexpression systems or non-specific silencing methods, these knockout cell lines provide a clear and direct evaluation of receptor function. Additionally, their high fidelity allows for consistent results across experiments, thus enhancing the reliability of findings.

For researchers and clinicians alike, the OR8U8 Gene Knockout Cell Lines present a compelling opportunity to delve into the complexities of genetic influences on olfaction. By bridging molecular genetics with sensory biology, this product not only has the potential to spur scientific breakthroughs but also to enhance our understanding of olfactory mechanisms essential for health and disease.

Our company prides itself on delivering high-quality, innovative research tools that elevate scientific exploration. With a focus on precision and utility, we are dedicated to supporting the research community with cutting-edge products like the OR8U8 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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