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OR8J2 Knockout Cell Lines

Gene: OR8J2

Official Full Name: olfactory receptor family 8 subfamily J member 2 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25830 OR8J2 Knockout cell line (HeLa) Human OR8J2 1:3~1:6 Negative Online Inquiry
KO25831 OR8J2 Knockout cell line (HCT 116) Human OR8J2 1:2~1:4 Negative Online Inquiry
KO25832 OR8J2 Knockout cell line (HEK293) Human OR8J2 1:3~1:6 Negative Online Inquiry
KO25833 OR8J2 Knockout cell line (A549) Human OR8J2 1:3~1:4 Negative Online Inquiry

Background

OR8J2 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, designed specifically to enable the study of the OR8J2 gene, a member of the olfactory receptor gene family implicated in the sensory perception of smells. These cell lines are engineered using precise gene editing technologies, such as CRISPR/Cas9, to create stable knockouts that effectively deactivate the OR8J2 gene. This knockout approach allows researchers to investigate the biochemical and physiological roles of this olfactory receptor, providing insights into sensory signaling pathways and their implications in health and disease.

The key function of these cell lines lies in their ability to facilitate a range of experimental applications, from basic research into olfactory mechanisms to pharmacological studies that may explore therapeutics targeting olfactory disorders or dysfunctions. By analyzing the behavior of cells devoid of the OR8J2 receptor, researchers can elucidate how sensory information is processed and how variations in olfactory receptor functionality may contribute to metabolic or neurodegenerative diseases.

One significant advantage of the OR8J2 Gene Knockout Cell Lines is their specificity and reproducibility; researchers can obtain consistent results across multiple experiments, increasing the reliability of their findings. Compared to other methods of studying gene function, such as temporary knockdowns or overexpression systems, these knockout cell lines provide a more stable and robust model that reflects the natural pathophysiology.

For researchers and clinicians alike, the value of the OR8J2 Gene Knockout Cell Lines is clear: they offer a unique opportunity to decipher the complex biology of olfaction and its broader implications in human health. This product will be especially valuable for those looking to ground their hypotheses in robust genetic evidence, paving the way for innovative therapies and molecular interventions.

Our company is committed to advancing scientific research through high-quality biological products, and our expertise in genetic engineering ensures that our OR8J2 Gene Knockout Cell Lines meet the highest standards for experimental reliability and reproducibility. We are dedicated to supporting the scientific community with tools that drive discovery and propel understanding of critical biological processes.

Please note that all services are for research use only. Not intended for any clinical use.

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