Gene: OR52D1
Official Full Name: olfactory receptor family 52 subfamily D member 1provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25821 | OR52D1 Knockout cell line (HCT 116) | Human | OR52D1 | 1:2~1:4 | Negative | Online Inquiry |
OR52D1 Gene Knockout Cell Lines are a revolutionary biological tool designed to facilitate in-depth research on the olfactory receptor gene OR52D1. Created through advanced CRISPR-Cas9 genome editing technology, these specialized cell lines feature a complete knockout of the OR52D1 gene, effectively providing a unique platform to elucidate the physiological functions and signaling pathways associated with this receptor. By removing the gene, researchers are granted the opportunity to study the receptor's role in olfactory transduction and its implications in sensory perception disorders.
The primary function of these knockout cell lines lies in their capacity to serve as a control model, enabling investigators to accurately assess the impact of OR52D1 on cellular responses, including receptor-ligand interactions, downstream signaling cascades, and gene expression profiles. This mechanistic insight is crucial for understanding how variations in olfactory receptors may influence human behavior and health.
The scientific importance of OR52D1 Gene Knockout Cell Lines extends across various disciplines, from neurobiology to pharmacology. In clinical settings, they can help identify therapeutic targets for conditions such as anosmia or other sensory processing disorders. In research, these cell lines provide a powerful tool for drug development and for probing novel olfactory signaling pathways, which may lead to breakthroughs in therapeutic interventions.
Compared to alternative models, OR52D1 Gene Knockout Cell Lines offer unmatched specificity and a more straightforward approach to studying receptor functions without the confounding effects of intact gene expression. Their reliability and precision stand out, making them a superior choice for researchers seeking to explore the complexities of olfactory signaling.
For scholars and clinicians focused on advancing the understanding of sensory biology and developing targeted therapeutic approaches, OR52D1 Gene Knockout Cell Lines represent an invaluable asset. They empower researchers to make significant strides in both basic and applied science.
Our company's commitment to delivering cutting-edge biological products is underscored by our expertise in genetic engineering and cell line development, ensuring that we provide the highest quality tools for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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