Gene: OR51M1
Official Full Name: olfactory receptor family 51 subfamily M member 1provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15443 | OR51M1 Knockout cell line (HCT 116) | Human | OR51M1 | 1:2~1:4 | Negative | Online Inquiry |
OR51M1 Gene Knockout Cell Lines represent a pivotal advancement in the study of olfactory receptors and their significant role in chemosensation. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of the OR51M1 gene, enabling researchers to explore the physiological and molecular functions associated with this olfactory receptor. The precise modification of the genome allows for in-depth analysis of orophysiological processes, thus elucidating the contributions of OR51M1 in various biological systems.
The functional relevance of OR51M1 in olfactory signaling pathways underlies its critical role in the perception of environmental cues and potential implications in behavioral responses. By harnessing the capabilities of these knockout cell lines, researchers can dissect signaling cascades, cellular responses to odorants, and the receptor's involvement in pathophysiological conditions, such as neurological disorders and metabolic diseases.
Compared to traditional gene silencing methods, this gene knockout approach offers unparalleled specificity and efficiency in targeting the OR51M1 receptor, minimizing off-target effects commonly associated with RNA interference techniques. Furthermore, the availability of validated, stable cell lines facilitates reproducibility in experiments, an essential aspect that enhances scientific rigor.
The value of OR51M1 Gene Knockout Cell Lines extends beyond academic research; they are instrumental for pharmaceutical development, enabling drug discovery strategies that focus on the modulation of olfactory pathways for therapeutic benefits. For clinicians and researchers who aim to expand the frontiers of olfactory science, these cell lines provide an essential tool to elucidate receptor biology and contribute to translational research.
With a commitment to excellence in biological products, our company harnesses decades of expertise in genetic engineering and cell line development to provide unparalleled research tools, ensuring scientists achieve their objectives efficiently and effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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