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OR1D4 Knockout Cell Lines

Gene: OR1D4

Official Full Name: olfactory receptor family 1 subfamily D member 4provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34207 OR1D4 Knockout cell line (HeLa) Human OR1D4 1:3~1:6 Negative Online Inquiry
KO34208 OR1D4 Knockout cell line (HCT 116) Human OR1D4 1:2~1:4 Negative Online Inquiry
KO34209 OR1D4 Knockout cell line (HEK293) Human OR1D4 1:3~1:6 Negative Online Inquiry
KO34210 OR1D4 Knockout cell line (A549) Human OR1D4 1:3~1:4 Negative Online Inquiry

Background

OR1D4 Gene Knockout Cell Lines are engineered cellular models in which the OR1D4 gene has been selectively disrupted using advanced CRISPR/Cas9 gene-editing technology. This product provides researchers with a powerful tool to study the biological functions and pathways influenced by OR1D4, a gene implicated in various physiological processes, including olfactory signal transduction and potential roles in metabolic regulation.

The key function of these knockout cell lines lies in their ability to elucidate the gene’s role by contrasting cellular behavior in OR1D4-absent environments to wild-type controls. Researchers can employ these cell lines in a variety of assays, including cell signaling, metabolic studies, and drug response evaluations, enabling a comprehensive understanding of OR1D4's effects on cellular physiology and pathology. The absence of this gene offers a unique opportunity to investigate its contributions in models of human disease, particularly in metabolic disorders and olfactory dysfunctions.

OR1D4 Gene Knockout Cell Lines hold significant scientific importance in both basic and applied research. They have widespread applicability in academic and clinical settings, such as drug discovery and development, disease modeling, and therapeutic intervention strategies. By using these specialized cell lines, researchers can generate insights that could potentially lead to novel treatments or interventions targeted at conditions linked with OR1D4 modulation.

The advantages of OR1D4 Gene Knockout Cell Lines over alternative methods include their ease of use, reproducibility, and the specificity of gene disruption, which allows for precise functional analysis. Unlike transient knockdown techniques, these stable cell lines provide a more consistent model for long-term studies, eliminating variables that could arise from temporary effects.

For researchers and clinicians alike, the ability to obtain clear, accurate data on OR1D4's role in health and disease is invaluable, enhancing the overall understanding of related biological processes. Furthermore, our company specializes in providing high-quality, well-characterized genetic models, ensuring that our customers receive reliable products to advance their research endeavors. With our expertise in developing gene knockout models, we are committed to supporting scientific innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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