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OBI1 Knockout Cell Lines

Gene: OBI1

Official Full Name: ORC ubiquitin ligase 1provided by HGNC

Gene Summary: Enables chromatin binding activity and ubiquitin-protein transferase activity. Involved in protein autoubiquitination; protein monoubiquitination; and regulation of DNA replication. Located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15545 OBI1 Knockout cell line (HeLa) Human OBI1 1:3~1:6 Negative Online Inquiry
KO15546 OBI1 Knockout cell line (HCT 116) Human OBI1 1:2~1:4 Negative Online Inquiry
KO15547 OBI1 Knockout cell line (HEK293) Human OBI1 1:3~1:6 Negative Online Inquiry
KO15548 OBI1 Knockout cell line (A549) Human OBI1 1:3~1:4 Negative Online Inquiry

Background

The OBI1 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the expression of the OBI1 gene, a crucial component in various biological pathways. This advanced tool serves as an indispensable asset for researchers aiming to dissect the functions of the OBI1 gene and its contributions to cellular processes such as cell signaling, metabolism, and disease manifestation. By employing CRISPR-Cas9 technology, these cell lines allow for precise edits in the genome, effectively enabling the inactivation of the OBI1 gene and facilitating a clearer understanding of its role in cellular dynamics.

Key functions of the OBI1 Gene Knockout Cell Lines include the ability to monitor phenotypic changes resulting from gene disruption, allowing for the exploration of possible compensatory mechanisms employed by the cells. Researchers can leverage these models to study differential gene expression, investigate metabolic shifts, and assess responses to pharmacological treatments in the absence of OBI1. This line of inquiry is particularly pertinent in studying conditions where OBI1 is implicated, such as metabolic disorders and cancers.

In terms of scientific importance, the OBI1 Gene Knockout Cell Lines open new avenues for research and therapeutic development. These cell lines not only provide valuable insights into gene function but also serve as a platform for high-throughput drug screening, making them perfect for clinical applications aimed at discovering novel treatments for diseases associated with OBI1 dysregulation.

What sets the OBI1 Gene Knockout Cell Lines apart from alternative models is their unique creation using rigorous validation processes, ensuring consistent and reproducible results. Developed under stringent quality control measures, these cell lines are optimized for various experimental conditions, facilitating ease of use and integration into diverse research protocols.

For researchers and clinicians, the value of utilizing the OBI1 Gene Knockout Cell Lines lies in their capacity to provide clear and actionable insights into gene function and disease mechanisms, ultimately supporting the development of targeted therapies. With a commitment to innovation and excellence, our company specializes in providing high-quality biological products for the research community, ensuring that scientists have the tools necessary to advance their investigations and contribute to breakthroughs in biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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