Gene: NTNG1
Official Full Name: netrin G1provided by HGNC
Gene Summary: This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30275 | NTNG1 Knockout cell line (HeLa) | Human | NTNG1 | 1:3~1:6 | Negative | Online Inquiry |
NTNG1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the NTNG1 gene, a critical player in neuronal development and guidance. These cell lines serve as an invaluable resource for researchers aiming to dissect the molecular pathways involved in neurodevelopmental processes and understanding neurodegenerative conditions. By utilizing CRISPR/Cas9 gene-editing technology, NTNG1 function has been specifically eliminated, allowing for precise examination of its role within neuronal signaling networks.
The primary mechanism underlying the utility of NTNG1 knockout cell lines is their ability to provide a controlled environment to assess how the absence of NTNG1 affects neuronal phenotype, growth, and connectivity. This offers researchers insight into the gene’s functional implications on synaptogenesis and neuroplasticity, and sheds light on potential disruptions that may contribute to diseases such as schizophrenia or autism spectrum disorders.
These knockout cell lines are of paramount scientific importance in both basic research and clinical settings. They facilitate Investigations into gene function, drug discovery, and the design of potential therapeutic interventions aimed at restoring normal neuronal function. Unlike traditional methods that may involve the use of broad-spectrum inhibitors, these cell lines allow for targeted studies that can lead to more specific findings and, ultimately, more effective treatment prospects.
NTNG1 Gene Knockout Cell Lines outshine alternative models by providing a validated platform with high specificity for various applications, including high-throughput screening and phenotypic assays. Their robustness in reproducibility and ease of cultivation makes them an ideal choice for teams seeking reliable data that translates effectively into clinical relevance.
In a world where precision medicine is increasingly becoming the standard, the NTNG1 Gene Knockout Cell Lines offer researchers and clinicians an opportunity to unlock new avenues of investigation and therapeutic discovery. Our company’s deep commitment to advancing genetic engineering technologies ensures that our products are at the forefront of innovation, tailored for the rigorous demands of modern bioscience research.
Please note that all services are for research use only. Not intended for any clinical use.
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