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NT5DC1 Knockout Cell Lines

Gene: NT5DC1

Official Full Name: 5'-nucleotidase domain containing 1provided by HGNC

Gene Summary: While the exact function of the protein encoded by this gene is not known, it belongs to the 5'(3')-deoxyribonucleotidase family. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27524 NT5DC1 Knockout cell line (HeLa) Human NT5DC1 1:3~1:6 Negative Online Inquiry
KO27525 NT5DC1 Knockout cell line (HCT 116) Human NT5DC1 1:2~1:4 Negative Online Inquiry
KO27526 NT5DC1 Knockout cell line (HEK293) Human NT5DC1 1:3~1:6 Negative Online Inquiry
KO27527 NT5DC1 Knockout cell line (A549) Human NT5DC1 1:3~1:4 Negative Online Inquiry

Background

NT5DC1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the NT5DC1 gene, which is crucial in purine metabolism and cellular signaling pathways. This genetic alteration allows researchers to investigate the functional consequences of NT5DC1 depletion, enabling them to explore its role in various biological processes, including cellular proliferation, differentiation, and response to stress. Utilizing CRISPR-Cas9 technology, these knockout cell lines provide a precise and efficient way to study gene function and its impact on cellular behavior.

The key functions of the NT5DC1 gene involve its participation in the hydrolysis of nucleotides, which is vital for maintaining nucleotide pools and regulating metabolic homeostasis. By knocking out NT5DC1, researchers can elucidate pathways influenced by altered nucleotide metabolism, thus providing insights into cancer biology, metabolic disorders, and drug responses. These models are also instrumental in drug discovery and the evaluation of therapeutic interventions, as they allow for the testing of compounds that target NT5DC1-dependent pathways.

The scientific importance of NT5DC1 Gene Knockout Cell Lines extends into numerous research and clinical applications, including cancer research, where the gene's role in tumor growth and metastasis is under investigation. Additionally, these cell lines can be utilized to assess the efficacy of novel therapies aimed at modulating purine metabolism, offering a platform for translational studies.

Compared to traditional cell lines, the NT5DC1 knockout models provide distinct advantages, including enhanced specificity in studying NT5DC1-related processes and a higher degree of reproducibility in experimental outcomes. Moreover, these cell lines facilitate the exploration of compensatory mechanisms that may arise upon gene inactivation, enriching the understanding of gene-gene interactions in a cellular context.

For researchers and clinicians alike, the NT5DC1 Gene Knockout Cell Lines represent a valuable tool for advancing knowledge in molecular biology and therapeutic development. They empower scientists to discover new biological insights and therapeutic strategies, significantly contributing to the fields of genetics and biomedicine.

Our company specializes in the development of high-quality cell lines and gene-editing tools, backed by extensive expertise and commitment to advancing life science research. We strive to provide researchers with the resources they need to push the boundaries of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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