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NT5C2 Knockout Cell Lines

Gene: NT5C2

Official Full Name: 5'-nucleotidase, cytosolic IIprovided by HGNC

Gene Summary: This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30076 NT5C2 Knockout cell line (HeLa) Human NT5C2 1:3~1:6 Negative Online Inquiry
KO30077 NT5C2 Knockout cell line (HCT 116) Human NT5C2 1:2~1:4 Negative Online Inquiry
KO30078 NT5C2 Knockout cell line (HEK293) Human NT5C2 1:3~1:6 Negative Online Inquiry
KO30079 NT5C2 Knockout cell line (A549) Human NT5C2 1:3~1:4 Negative Online Inquiry

Background

NT5C2 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to lack the NT5C2 gene, which encodes for the enzyme nucleoside triphosphate diphosphohydrolase. This enzyme plays a critical role in nucleotide metabolism by regulating the intracellular levels of nucleosides and nucleotides. The absence of NT5C2 can significantly alter cellular responses to metabolic stresses, making these knockout cell lines valuable tools for studying the implications of altered nucleotide pools in various biological processes.

These cell lines function as a platform for elucidating the roles of the NT5C2 gene in cancer biology, metabolic disorders, and drug resistance mechanisms. By observing changes in cellular behavior, researchers can understand how NT5C2 contributes to cellular homeostasis and its potential involvement in pathological conditions. With the ability to manipulate metabolic pathways in real-time, scientists can employ these knockout models to explore therapeutic interventions targeting nucleotide metabolism, thereby advancing our understanding of human disease.

The scientific importance of NT5C2 Gene Knockout Cell Lines extends into both research and clinical applications. In research settings, they are invaluable for dissecting the molecular mechanisms involving nucleotide metabolism and its relationship with cellular processes such as proliferation and apoptosis. Clinically, insights gained from these models may lead to the development of novel treatment strategies targeting nucleotide metabolism in cancers and other disorders.

What sets our NT5C2 Gene Knockout Cell Lines apart from traditional cell models is the precision of their design, allowing for clear delineation of the gene's functional role without compensatory effects from homologous genes. Furthermore, these models maintain genetic stability and reproducibility, ensuring high-quality data for experimental studies.

For researchers and clinicians alike, the ability to study the NT5C2 gene in a controlled environment opens up new avenues for targeted therapy development and a deeper understanding of cellular mechanics. Our company, with expertise in gene editing technologies and a commitment to advancing biomedical research, offers a reliable resource for cutting-edge cell line products. By leveraging our innovative gene knockout models, researchers can unlock new understanding and devise innovative treatments that could improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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