Gene: NSMF
Official Full Name: NMDA receptor synaptonuclear signaling and neuronal migration factorprovided by HGNC
Gene Summary: The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28483 | NSMF Knockout cell line (HeLa) | Human | NSMF | 1:3~1:6 | Negative | Online Inquiry |
KO28484 | NSMF Knockout cell line (HCT 116) | Human | NSMF | 1:2~1:4 | Negative | Online Inquiry |
KO28485 | NSMF Knockout cell line (HEK293) | Human | NSMF | 1:3~1:6 | Negative | Online Inquiry |
KO28486 | NSMF Knockout cell line (A549) | Human | NSMF | 1:3~1:4 | Negative | Online Inquiry |
NSMF Gene Knockout Cell Lines are specialized, genetically engineered cell lines designed to facilitate the study of NSMF (Nuclear Suppressor of Methylation and Fragmentation) gene function in a controlled laboratory setting. By employing CRISPR-Cas9 technology, these cell lines exhibit targeted gene knockouts that allow researchers to investigate the downstream effects of NSMF alteration on cellular processes, including gene expression regulation, cellular differentiation, and stress response mechanisms.
The primary function of NSMF Gene Knockout Cell Lines is to enable the exploration of the biological pathways influenced by NSMF. These cell lines serve as a platform to dissect the role of NSMF in various physiological and pathological conditions. The mechanism involves the precise editing of the NSMF gene, leading to the loss of its function, thereby providing insights into the gene's contribution to tissue development and disease progression. Researchers can utilize these knockout models to assess changes in signaling pathways, metabolic shifts, or cellular behavior across different experimental contexts.
The scientific importance of NSMF Gene Knockout Cell Lines is underscored by their applications in both basic and translational research. They are invaluable tools in understanding complex diseases, including cancer, neurodegeneration, and metabolic disorders. By elucidating the molecular mechanisms mediated by NSMF, researchers can identify potential therapeutic targets or biomarkers, paving the way for novel interventions in clinical settings.
Compared to traditional cell lines or non-targeted knockout methods, NSMF Gene Knockout Cell Lines offer several advantages. The precision offered by CRISPR technology minimizes off-target effects, ensuring the reliability of experimental results. Additionally, these cell lines are fully characterized and validated, saving researchers time and resources typically spent on the initial stages of model development.
For researchers and clinicians, the NSMF Gene Knockout Cell Lines represent an essential resource that empowers them to delve deeper into genetic regulation mechanisms and disease models. The unique insights gained from these models can provide a competitive edge in research innovation and discovery.
As a leading provider in genetic engineering and biological products, our company brings extensive expertise in developing high-fidelity cell line models that meet rigorous scientific standards, allowing you to advance your research with confidence in the tools at your disposal.
Please note that all services are for research use only. Not intended for any clinical use.
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