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NR2F2 Knockout Cell Lines

Gene: NR2F2

Official Full Name: nuclear receptor subfamily 2 group F member 2provided by HGNC

Gene Summary: This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06572 NR2F2 Knockout cell line (HeLa) Human NR2F2 1:3~1:6 Negative Online Inquiry
KO06573 NR2F2 Knockout cell line (HCT 116) Human NR2F2 1:2~1:4 Negative Online Inquiry
KO06574 NR2F2 Knockout cell line (HEK293) Human NR2F2 1:3~1:6 Negative Online Inquiry
KO06575 NR2F2 Knockout cell line (A549) Human NR2F2 1:3~1:4 Negative Online Inquiry

Background

NR2F2 Gene Knockout Cell Lines represent a cutting-edge biological tool designed for advanced genetic research and therapeutic applications. These cell lines are engineered to have a targeted deletion of the NR2F2 gene, which plays a crucial role in various cellular processes, including differentiation, metabolism, and development. By knocking out this gene, researchers can investigate the functional implications of its absence and explore its contributions to specific biological pathways and diseases.

The primary mechanism of these cell lines is based on CRISPR-Cas9 technology, which allows precise editing of the genome. This approach ensures a complete ablation of NR2F2, enabling the study of its role in signaling pathways, gene expression regulation, and interactions with other transcription factors. Importantly, the NR2F2 knockout cell lines are invaluable for elucidating the gene's implications in disease models and uncovering potential therapeutic targets in conditions such as cancer and cardiovascular diseases.

In research and clinical settings, these cell lines facilitate high-throughput screening for drug discovery, exploring the role of NR2F2 in drug response, and understanding its involvement in pathogenetic mechanisms. The specificity and reliability of these cell lines distinguish them from other methods, such as RNA interference, which may produce off-target effects or incomplete silencing of gene expression.

These knockout cell lines offer unique advantages, including enhanced reproducibility, versatile application potential, and the possibility for subsequent genetic rescues. Their utilization can significantly streamline research workflows, providing precise models that reflect the deletion of NR2F2.

For researchers and clinicians, the NR2F2 Gene Knockout Cell Lines offer invaluable insights into genetic regulation and a pathway to novel therapeutic approaches. By integrating these models into their research frameworks, users can accelerate findings and contribute to innovations in genomics and personalized medicine.

Our company is dedicated to advancing biological research through high-quality, rigorously validated products. We specialize in genetic editing technologies, ensuring our offerings meet the exacting standards of scientific professionalism and efficacy, empowering researchers to unlock new dimensions of understanding in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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