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NR2F1 Knockout Cell Lines

Gene: NR2F1

Official Full Name: nuclear receptor subfamily 2 group F member 1provided by HGNC

Gene Summary: The protein encoded by this gene is a nuclear hormone receptor and transcriptional regulator. The encoded protein acts as a homodimer and binds to 5'-AGGTCA-3' repeats. Defects in this gene are a cause of Bosch-Boonstra optic atrophy syndrome (BBOAS). [provided by RefSeq, Apr 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04269 NR2F1 Knockout cell line (HeLa) Human NR2F1 1:3~1:6 Negative Online Inquiry
KO04270 NR2F1 Knockout cell line (HCT 116) Human NR2F1 1:2~1:4 Negative Online Inquiry
KO04271 NR2F1 Knockout cell line (HEK293) Human NR2F1 1:3~1:6 Negative Online Inquiry
KO04272 NR2F1 Knockout cell line (A549) Human NR2F1 1:3~1:4 Negative Online Inquiry

Background

NR2F1 Gene Knockout Cell Lines represent a significant advancement in the field of genetic research and molecular biology. These cell lines are specifically engineered to lack the NR2F1 gene, which plays a critical role in the regulation of gene expression and cellular differentiation. This gene is associated with various developmental processes and pathologies, making its knockout an invaluable tool for studying its function and impact on cellular mechanisms.

The NR2F1 gene encodes a transcription factor involved in orchestrating the development of the central nervous system and other tissues. By utilizing these knockout cell lines, researchers can explore the downstream effects of NR2F1 absence on signaling pathways, gene expression profiles, and cellular behaviors such as proliferation, apoptosis, and differentiation. This provides insights into developmental biology and the molecular underpinnings of diseases, including neurodevelopmental disorders and certain cancers.

In terms of scientific significance, NR2F1 Gene Knockout Cell Lines are crucial for investigating the roles of NR2F1 in health and disease. They facilitate the understanding of genetic interactions and regulatory networks that could potentially lead to novel therapeutic targets. In clinical and research settings, these cell lines are an essential resource for drug discovery, biomarker identification, and functional studies, providing a reliable model to test hypotheses regarding NR2F1's function.

Compared to alternative cell lines, NR2F1 knockout models offer specific advantages by directly enabling the study of the gene's deletion effects in a controlled environment, thus minimizing variability and enhancing reproducibility. Furthermore, these knockout lines allow for high-throughput screening applications, making them an attractive option for laboratories focused on genetic research.

The value of NR2F1 Gene Knockout Cell Lines extends beyond their research utility; they empower scientists and clinicians with the tools needed to unravel complex biological questions and develop potential interventions. Our company, dedicated to supporting groundbreaking discoveries in the biological sciences, specializes in producing high-quality genetic models that enhance research outcomes and facilitate the progression of scientific knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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