Gene: NME7
Official Full Name: NME/NM23 family member 7provided by HGNC
Gene Summary: This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26944 | NME7 Knockout cell line (HeLa) | Human | NME7 | 1:3~1:6 | Negative | Online Inquiry |
KO26945 | NME7 Knockout cell line (HCT 116) | Human | NME7 | 1:2~1:4 | Negative | Online Inquiry |
KO26946 | NME7 Knockout cell line (HEK293) | Human | NME7 | 1:3~1:6 | Negative | Online Inquiry |
KO26947 | NME7 Knockout cell line (A549) | Human | NME7 | 1:3~1:4 | Negative | Online Inquiry |
NME7 Gene Knockout Cell Lines are genetically engineered cell lines where the NME7 gene has been deliberately disrupted or "knocked out," enabling researchers to explore the specific biological functions and pathways associated with this gene. This product facilitates comprehensive studies into cellular processes including, but not limited to, cell cycle regulation, differentiation, and metabolic pathways, as NME7 is associated with nucleotide metabolism and cellular stress responses.
The primary mechanism of NME7 gene knockout involves the use of CRISPR-Cas9 technology or other gene-editing techniques to create precise mutations that prevent NME7 protein expression. This disruption allows scientists to investigate phenotypic changes and elucidates the role of NME7 in various cellular contexts. By analyzing these knockout cell lines, researchers can gain insights into the gene’s contributions to disease mechanisms, particularly in oncology and metabolic disorders, thus opening avenues for therapeutic interventions and drug development.
In terms of scientific importance, NME7 Gene Knockout Cell Lines can serve as a valuable resource for functional genomics and translational research. Their applications in both academic and industrial laboratories include drug screening, biochemical assays, and understanding gene-environment interactions. Compared to other gene knockout systems, NME7 knockout lines provide a unique opportunity to study a less-explored gene, which may yield novel findings relevant to previously established theories.
The advantages of using NME7 Gene Knockout Cell Lines lie in their specificity and ease of use. Researchers benefit from a reliable model that reflects realistic biological processes, increases reproducibility in experimental results, and saves time in establishing customized cell lines. Furthermore, by utilizing our product, researchers can leverage the expertise of our company, renowned for its commitment to quality and innovation in genetic engineering solutions. We offer a robust supporting infrastructure, ensuring users have access to comprehensive technical support and detailed protocols, enhancing the overall research experience.
Please note that all services are for research use only. Not intended for any clinical use.
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