Gene: NIPAL1
Official Full Name: NIPA like domain containing 1provided by HGNC
Gene Summary: Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21791 | NIPAL1 Knockout cell line (HeLa) | Human | NIPAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO21792 | NIPAL1 Knockout cell line (HCT 116) | Human | NIPAL1 | 1:2~1:4 | Negative | Online Inquiry |
KO21793 | NIPAL1 Knockout cell line (HEK293) | Human | NIPAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO21794 | NIPAL1 Knockout cell line (A549) | Human | NIPAL1 | 1:3~1:4 | Negative | Online Inquiry |
NIPAL1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the function of the NIPAL1 gene, which encodes a protein implicated in various cellular processes, including lipid metabolism and cellular stress responses. By utilizing CRISPR/Cas9 gene editing technology, these cell lines have been developed to lack functional NIPAL1 protein, allowing researchers to investigate the downstream effects of NIPAL1 disruption on cellular behavior, signaling pathways, and metabolic processes.
The primary mechanism of these knockout cell lines is the precise inactivation of the NIPAL1 gene, leading to the complete absence of its protein product. This loss of function facilitates in-depth studies into the gene's role in health and disease, particularly in the context of metabolic disorders and conditions associated with cellular stress. As such, NIPAL1 Gene Knockout Cell Lines serve as vital tools in elucidating disease mechanisms, drug discovery, and potential therapeutic interventions, thus playing a crucial role in translational medicine.
Compared to alternative models such as wild-type cell lines or transient transfection systems, the NIPAL1 knockout cell lines provide a stable and reproducible environment for long-term studies. Researchers benefit from the consistent genetic background, allowing for accurate comparisons and the exploration of complex biological interactions without the variability introduced by transitory expression systems.
The unique value of NIPAL1 Gene Knockout Cell Lines lies in their capacity to accelerate research in metabolic disease pathways and enhance our understanding of cellular function under stress. For clinicians and researchers focused on the underlying genetic factors of diseases, these models offer critical insight that can inform future therapeutic strategies and patient management.
Our company leverages extensive expertise in genetic engineering and cellular biology to provide high-quality, reliable, and accessible biological products like the NIPAL1 Gene Knockout Cell Lines, empowering researchers to make significant advancements in their discoveries and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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