Gene: NETO2
Official Full Name: neuropilin and tolloid like 2provided by HGNC
Gene Summary: This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25651 | NETO2 Knockout cell line (HeLa) | Human | NETO2 | 1:3~1:6 | Negative | Online Inquiry |
KO25652 | NETO2 Knockout cell line (HCT 116) | Human | NETO2 | 1:2~1:4 | Negative | Online Inquiry |
KO25653 | NETO2 Knockout cell line (HEK293) | Human | NETO2 | 1:3~1:6 | Negative | Online Inquiry |
KO25654 | NETO2 Knockout cell line (A549) | Human | NETO2 | 1:3~1:4 | Negative | Online Inquiry |
NETO2 Gene Knockout Cell Lines are specifically engineered cellular models designed to disrupt the NETO2 gene, which is implicated in various physiological processes, including neurodevelopment and synaptic function. By employing CRISPR/Cas9 technology, these cell lines facilitate precise gene editing, allowing for the study of the gene's function and its contribution to cellular pathways.
The primary mechanism of action involves the targeted alteration of the NETO2 gene, leading to a loss-of-function phenotype. This allows researchers to investigate the physiological and pathological implications of NETO2 deficiency in cellular environments that mimic in vivo conditions. As such, these knockout cell lines serve as invaluable tools for understanding the underlying mechanisms of neurobiology and related disorders, providing insights into synaptic transmission and neural circuit formation.
The scientific importance of NETO2 Gene Knockout Cell Lines extends beyond basic research; they can be employed in drug discovery and therapeutic explorations aimed at neurological diseases. By offering a human-relevant model for studying genetic contributions to neurodevelopmental disorders, these cell lines empower both academic and pharmaceutical researchers in their quest to develop novel therapeutic strategies.
What sets NETO2 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility, minimizing off-target effects that can confound experimental results. Additionally, they require no prior knowledge of gene characteristics, making them accessible for a wide range of research applications.
These innovative cell lines are not only pivotal for enhancing our understanding of gene function but are also instrumental in the translation of findings into clinical practice. For researchers and clinicians pursuing cutting-edge neurobiological inquiries, NETO2 Gene Knockout Cell Lines represent a transformative resource.
At our company, we are committed to delivering high-quality biological products, backed by rigorous scientific validation and extensive expertise in genetic editing technologies. This dedication ensures that our NETO2 Gene Knockout Cell Lines meet the highest standards for reliability and effectiveness in research applications.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.