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NEMF Knockout Cell Lines

Gene: NEMF

Official Full Name: nuclear export mediator factorprovided by HGNC

Gene Summary: This gene encodes a component of the ribosome quality control complex. The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor suppressor. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33533 NEMF Knockout cell line (HeLa) Human NEMF 1:3~1:6 Negative Online Inquiry
KO33534 NEMF Knockout cell line (HCT 116) Human NEMF 1:2~1:4 Negative Online Inquiry
KO33535 NEMF Knockout cell line (HEK293) Human NEMF 1:3~1:6 Negative Online Inquiry
KO33536 NEMF Knockout cell line (A549) Human NEMF 1:3~1:4 Negative Online Inquiry

Background

NEMF Gene Knockout Cell Lines represent a breakthrough in cellular research, specifically designed to facilitate the comprehensive study of gene function and regulation. These cell lines have been genetically engineered to completely inactivate the NEMF gene, which encodes the NEMF protein implicated in various biological processes, including protein homeostasis and degradation pathways. By utilizing CRISPR-Cas9 gene-editing technology, these knockout cell lines allow researchers to create a controlled environment for analyzing the phenotypic consequences of NEMF gene loss.

The key mechanisms of the NEMF Gene Knockout Cell Lines revolve around the complete disruption of NEMF expression, providing a unique platform to study alterations in cellular pathways that are influenced by this protein. This facilitates research into diseases linked to protein misfolding, cellular stress responses, and their implications in pathology, including cancer and neurodegenerative disorders.

From a scientific standpoint, NEMF Gene Knockout Cell Lines are invaluable tools in both basic and translational research. These cell lines can streamline drug discovery processes, identification of new therapeutic targets, and the elucidation of disease mechanisms at a cellular level. By offering a clear and reproducible means to study the effects of gene knockout, these cell lines enable researchers to gather robust data that advances understanding of complex biological systems.

Compared to alternatives such as transient knockdown assays, NEMF Gene Knockout Cell Lines provide stable and long-term gene inactivation, which leads to more reliable experimental outcomes. Their ease of maintenance and consistency in experiments makes them a preferred choice among researchers looking for high-quality solutions.

In conclusion, NEMF Gene Knockout Cell Lines stand out as a critical resource for academics and clinicians alike, facilitating groundbreaking research and the development of new treatments. With our company’s extensive expertise in gene editing technology and commitment to quality biological products, we are proud to support researchers in achieving their scientific goals with these advanced cell lines.

Please note that all services are for research use only. Not intended for any clinical use.

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