Gene: NDFIP1
Official Full Name: Nedd4 family interacting protein 1provided by HGNC
Gene Summary: The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25927 | NDFIP1 Knockout cell line (HeLa) | Human | NDFIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO25928 | NDFIP1 Knockout cell line (HCT 116) | Human | NDFIP1 | 1:2~1:4 | Negative | Online Inquiry |
KO25929 | NDFIP1 Knockout cell line (HEK293) | Human | NDFIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO25930 | NDFIP1 Knockout cell line (A549) | Human | NDFIP1 | 1:3~1:4 | Negative | Online Inquiry |
NDFIP1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the NDFIP1 gene, a key player in various intracellular signaling pathways involved in immune responses and cellular homeostasis. These knockout cell lines serve as valuable tools for researchers investigating the specific roles of NDFIP1 in health and disease. By eliminating this gene, the cell lines allow scientists to gain a clearer understanding of the biological processes affected by NDFIP1, including its role in protein sorting, cell proliferation, and apoptosis regulation.
The primary function of these cell lines is to facilitate the study of NDFIP1's involvement in cellular signaling. This is achieved through various assays that assess changes in cellular responses when NDFIP1 is absent. Researchers can examine differences in cytokine production, immune cell activation, and responses to therapy, thus illuminating the gene's contributions to various diseases, including cancer and autoimmune disorders.
From a scientific standpoint, NDFIP1 Gene Knockout Cell Lines hold significant importance in both basic and translational research. They can be applied in preclinical studies aimed at developing targeted therapies for conditions linked to dysregulation of NDFIP1 functions. Furthermore, they offer insights into potential biomarkers for disease progression and treatment response, making them invaluable in clinical settings.
Compared to alternative models such as transient gene silencing or overexpression systems, these knockout cell lines provide a stable and long-lasting approach to studying gene function. They ensure greater reproducibility of results and can be used in various experimental designs, offering versatility that is not achievable with transient systems. Additionally, the ability to selectively target gene knockout facilitates the exploration of compensatory mechanisms that may interfere with therapeutic strategies.
For researchers, clinicians, and biotech companies, the value of NDFIP1 Gene Knockout Cell Lines lies in their robustness and the profound insights they provide into the molecular underpinnings of disease. By using these models, researchers can produce more reliable data that aids in the progression from laboratory findings to clinical applications.
With decades of experience in the field of genetic engineering and an unwavering commitment to advancing biological research, our company stands as a leader in providing high-quality knockout cell lines, ensuring that our clients have access to the best tools available for their innovative research efforts.
Please note that all services are for research use only. Not intended for any clinical use.
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