Gene: NCAPD3
Official Full Name: non-SMC condensin II complex subunit D3provided by HGNC
Gene Summary: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01735 | NCAPD3 Knockout cell line (HeLa) | Human | NCAPD3 | 1:3~1:6 | Negative | Online Inquiry |
KO01736 | NCAPD3 Knockout cell line (HCT 116) | Human | NCAPD3 | 1:2~1:4 | Negative | Online Inquiry |
KO01737 | NCAPD3 Knockout cell line (HEK293) | Human | NCAPD3 | 1:3~1:6 | Negative | Online Inquiry |
NCAPD3 Gene Knockout Cell Lines are a state-of-the-art biological research tool designed to facilitate genetic studies by allowing researchers to investigate the function of the NCAPD3 gene in various biological processes. This gene is integral to the orchestration of chromatin dynamics and has been implicated in critical cellular functions including cell division, differentiation, and response to stressors. The knockout cell lines are meticulously engineered to exhibit a complete loss of NCAPD3 expression, enabling researchers to explore the phenotypic and molecular consequences of gene deletion.
The primary function of NCAPD3 Gene Knockout Cell Lines revolves around their ability to mimic gene silencing in a controlled environment, enhancing our understanding of gene function and regulation. This knockout approach employs CRISPR-Cas9 technology, a powerful genome editing tool that allows for precise alterations in the DNA sequence. By leveraging these cell lines, researchers can perform high-throughput screening, investigate cellular pathways, and assess the impacts of NCAPD3 depletion on various cellular processes.
Scientific studies leveraging these knockout lines have broad applications, ranging from cancer research to the exploration of genetic disorders, offering a valuable platform for identifying potential therapeutic targets. In clinical settings, such insights can lead to the development of novel treatments and personalized medicine approaches that are tailored specifically to the genetic profiles of patients.
One of the unique advantages of NCAPD3 Gene Knockout Cell Lines is the specificity and reliability of their genetic alteration, ensuring consistent results across experiments. Compared to other gene knockout strategies, these cell lines offer researchers a well-characterized model system that significantly reduces variability and enhances reproducibility, which is crucial in scientific research.
The value of these cell lines extends to both academic and pharmaceutical research settings, as they possess the potential to accelerate the discovery of new biological insights. Researchers and clinicians can utilize NCAPD3 knockouts to dissect complex biological pathways, ultimately contributing to advances in understanding disease mechanisms.
At the forefront of biotechnological innovation, our company prides itself on our expertise in producing high-quality biological products, including NCAPD3 Gene Knockout Cell Lines. Our commitment to precision, reliability, and scientific excellence empowers researchers to make pivotal discoveries that can lead to transformative developments in medical science.
Please note that all services are for research use only. Not intended for any clinical use.
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