Gene: NANOS3
Official Full Name: nanos C2HC-type zinc finger 3provided by HGNC
Gene Summary: Enables enzyme activator activity. Involved in germ cell development; mRNA destabilization; and negative regulation of translation. Located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15878 | NANOS3 Knockout cell line (HeLa) | Human | NANOS3 | 1:3~1:6 | Negative | Online Inquiry |
KO15879 | NANOS3 Knockout cell line (A549) | Human | NANOS3 | 1:3~1:4 | Negative | Online Inquiry |
NANOS3 Gene Knockout Cell Lines represent a pioneering tool in genetic research, specifically designed to facilitate the study of germ cell development and gametogenesis by systematically suppressing the NANOS3 gene. These cell lines provide a reliable in vitro model that allows researchers to investigate the downstream effects of NANOS3 gene disruption, which plays a critical role in the maintenance of pluripotency and the regulation of germline stem cells.
The key mechanism of action involves the use of CRISPR-Cas9 technology, which precisely targets and inactivates the NANOS3 gene, leading to a knockout phenotype. This genetic alteration enables the exploration of various cellular processes, including cell differentiation, proliferation rates, and apoptosis in context to germ cell lineage commitment. The resulting phenotypic insights are invaluable for deciphering complex biological pathways that underpin fertility and reproductive health.
In scientific and clinical research settings, NANOS3 Gene Knockout Cell Lines are essential for advancing our understanding of reproductive biology and potential therapeutic targets for infertility treatments. Their application extends to drug discovery, where they may assist in screening compounds that modulate germ cell function, thereby paving the way for innovative fertility solutions.
What sets NANOS3 Gene Knockout Cell Lines apart from traditional gene manipulation techniques is their remarkable efficiency and specificity, reducing off-target effects and enabling researchers to obtain consistent and reproducible results. Additionally, the ease of use and scalability of these cell lines make them a superior choice for high-throughput screening applications.
For researchers and clinicians focused on reproductive health, the NANOS3 Gene Knockout Cell Lines are an indispensable asset, providing clarity and enhancing our understanding of crucial biological processes. With our company's extensive background in genetic research and unwavering commitment to quality, we ensure that our products empower scientists in their quest for breakthroughs in reproductive biology.
Please note that all services are for research use only. Not intended for any clinical use.
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