Gene: NANOS1
Official Full Name: nanos C2HC-type zinc finger 1provided by HGNC
Gene Summary: This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15880 | NANOS1 Knockout cell line (HeLa) | Human | NANOS1 | 1:3~1:6 | Negative | Online Inquiry |
KO15881 | NANOS1 Knockout cell line (HCT 116) | Human | NANOS1 | 1:2~1:4 | Negative | Online Inquiry |
KO15882 | NANOS1 Knockout cell line (HEK293) | Human | NANOS1 | 1:3~1:6 | Negative | Online Inquiry |
KO15883 | NANOS1 Knockout cell line (A549) | Human | NANOS1 | 1:3~1:4 | Negative | Online Inquiry |
NANOS1 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the in-depth investigation of the NANOS1 gene, which is integral in the regulation of germ cell development and differentiation. These cell lines have been meticulously crafted using state-of-the-art CRISPR-Cas9 technology to achieve precise deletion of the NANOS1 gene, thereby enabling researchers to study the functional consequences of its absence in a controlled environment.
The primary function of NANOS1 Gene Knockout Cell Lines lies in their ability to mimic impaired NANOS1 signaling pathways, offering insights into its role in embryonic development, fertility, and related disorders. These models allow scientists to assess altered pathways through transcriptomic and proteomic analyses, leading to a better understanding of the gene's biological significance and its involvement in diseases such as infertility or germ cell tumors.
In research and clinical settings, these cell lines serve as vital tools for drug screening, genetic studies, and therapeutic development. Their utilization can enhance the specificity and efficacy of experimental outcomes, providing robust data for both basic and translational research. Furthermore, they offer a platform to explore potential interventions that may restore normal function or ameliorate disease states associated with NANOS1 dysregulation.
What sets NANOS1 Gene Knockout Cell Lines apart from alternative models is their validated performance and reproducibility, paired with comprehensive support provided by our dedicated technical team. Researchers can rely on these cell lines for consistent results, which are crucial for reproducibility in scientific investigations.
In summary, NANOS1 Gene Knockout Cell Lines represent a cutting-edge resource for researchers and clinicians aiming to delve into the complexities of germ cell biology. Our expertise in genetic engineering and commitment to quality ensure that our product not only meets but exceeds the expectations of the scientific community, driving advancements in understanding key biological processes and therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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