Gene: NADSYN1
Official Full Name: NAD synthetase 1provided by HGNC
Gene Summary: Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15895 | NADSYN1 Knockout cell line (HeLa) | Human | NADSYN1 | 1:3~1:6 | Negative | Online Inquiry |
KO15896 | NADSYN1 Knockout cell line (HCT 116) | Human | NADSYN1 | 1:2~1:4 | Negative | Online Inquiry |
KO15897 | NADSYN1 Knockout cell line (HEK293) | Human | NADSYN1 | 1:3~1:6 | Negative | Online Inquiry |
KO15898 | NADSYN1 Knockout cell line (A549) | Human | NADSYN1 | 1:3~1:4 | Negative | Online Inquiry |
NADSYN1 Gene Knockout Cell Lines are specialized cellular models designed to study the specific roles of the NADSYN1 gene, which is critical in the synthesis of nicotinamide adenine dinucleotide (NAD) and essential metabolic pathways like energy production and cellular signaling. By employing a targeted CRISPR/Cas9 gene editing approach, these knockout cell lines facilitate the functional characterization of NADSYN1, enabling researchers to observe phenotypic changes that occur due to its absence.
The primary mechanism of these cell lines involves the disruption of the NADSYN1 gene, which leads to perturbations in NAD synthesis and consequently impacts metabolic processes. Researchers can use these models to investigate the gene's role in cellular metabolism, oxidative stress responses, and potential contribution to various diseases, including metabolic disorders and age-related pathologies.
Scientifically, NADSYN1 Gene Knockout Cell Lines are invaluable tools in both basic research and clinical settings, allowing for deeper insights into metabolic dysfunctions and the biological implications of NAD depletion. Their application ranges from drug discovery to understanding disease mechanisms, providing a platform for elucidating potential therapeutic strategies aimed at regulating NAD levels in various physiological and pathological contexts.
One of the key advantages of using NADSYN1 Gene Knockout Cell Lines is their specificity and high fidelity compared to traditional cell lines. The targeted gene knockout eliminates concerns associated with off-target effects commonly seen in less precise methods. Furthermore, these cell lines are rigorously validated to guarantee reproducibility, ensuring reliable results for experimental studies.
Researchers and clinicians focused on metabolic health and related diseases can significantly benefit from incorporating NADSYN1 Gene Knockout Cell Lines into their projects due to their ability to unravel complex biological mechanisms linked to NAD metabolism. The insights gained could inspire innovative therapeutic approaches to tackle metabolic disorders and enhance clinical outcomes.
Our company specializes in delivering high-quality biological products tailored to precise research needs. With a commitment to excellence and the advancement of scientific discovery, we support the research community with cutting-edge cell line technologies like the NADSYN1 Gene Knockout Cell Lines, designed for optimal usability and reliability in scientific exploration.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.