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NABP1 Knockout Cell Lines

Gene: NABP1

Official Full Name: nucleic acid binding protein 1provided by HGNC

Gene Summary: Single-stranded DNA (ssDNA)-binding proteins, such as OBFC2A, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage (Richard et al., 2008 [PubMed 18449195]).[supplied by OMIM, Jun 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15910 NABP1 Knockout cell line (HeLa) Human NABP1 1:3~1:6 Negative Online Inquiry
KO15911 NABP1 Knockout cell line (HCT 116) Human NABP1 1:2~1:4 Negative Online Inquiry
KO15912 NABP1 Knockout cell line (HEK293) Human NABP1 1:3~1:6 Negative Online Inquiry
KO15913 NABP1 Knockout cell line (A549) Human NABP1 1:3~1:4 Negative Online Inquiry

Background

NABP1 Gene Knockout Cell Lines are genetically engineered cell models designed to lack the expression of the NABP1 gene, which is crucial in various biological processes, including RNA metabolism and translation regulation. The knockout of this gene allows researchers to investigate its specific contributions to cellular functions, disease mechanisms, and therapeutic responses in a controlled manner.

These cell lines function by utilizing CRISPR-Cas9 gene-editing technology, which induces targeted double-strand breaks in the genomic DNA, effectively disrupting the NABP1 gene. As a result, the absence of NABP1 protein can be analyzed alongside various cellular pathways, facilitating insights into its role in oncogenesis, metabolic disorders, and other pathologies.

The scientific importance of NABP1 Gene Knockout Cell Lines lies in their versatile applications in both basic and translational research. These models provide critical insights into how NABP1 influences cell growth, proliferation, and response to stressors, thus contributing to our understanding of cancer biology and therapeutic resistance. Additionally, they hold potential for drug discovery, allowing for the identification of novel therapeutic targets implicated in diseases associated with NABP1 dysregulation.

Advantages of using NABP1 Gene Knockout Cell Lines compared to traditional cell models include their specificity and reliability in elucidating the functions of NABP1 without confounding effects from gene compensation or alternative splicing. Moreover, these knockout lines can be used alongside various high-throughput screening methods, making them invaluable for systematic investigations.

Researchers and clinicians seeking to enhance their understanding of NABP1-related pathways or developing targeted therapies will find these knockout cell lines indispensable. They not only streamline experimental design but also provide robust data, accelerating the progression of fundamental research towards clinical applications.

Our company possesses extensive expertise in providing high-quality, validated biological products, ensuring that our NABP1 Gene Knockout Cell Lines meet the rigorous standards necessary for cutting-edge research. By integrating innovative technology with an understanding of complex biological systems, we are committed to supporting the scientific community in advancing research and therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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