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NAA40 Knockout Cell Lines

Gene: NAA40

Official Full Name: N-alpha-acetyltransferase 40, NatD catalytic subunitprovided by HGNC

Gene Summary: Enables histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within lipid metabolic process. Located in centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15918 NAA40 Knockout cell line (HeLa) Human NAA40 1:3~1:6 Negative Online Inquiry
KO15919 NAA40 Knockout cell line (HCT 116) Human NAA40 1:2~1:4 Negative Online Inquiry
KO15920 NAA40 Knockout cell line (HEK293) Human NAA40 1:3~1:6 Negative Online Inquiry
KO15921 NAA40 Knockout cell line (A549) Human NAA40 1:3~1:4 Negative Online Inquiry

Background

NAA40 Gene Knockout Cell Lines represent a groundbreaking biotechnological advancement, enabling the targeted disruption of the NAA40 gene, which is crucial for the function of several cellular pathways, including protein translation and post-translational modifications. By employing CRISPR-Cas9 technology, these cell lines facilitate precise and efficient gene editing, allowing researchers to unravel the complex roles of NAA40 in cellular biology and pathophysiology.

The primary functionality of NAA40 Gene Knockout Cell Lines lies in their capacity to model gene function through the elimination of NAA40 expression. This allows for in-depth investigations into its contributions to processes such as ribosomal biogenesis, cell growth, and stress response. Cellular assays can be performed to evaluate phenotypic changes, assess metabolic alterations, and understand the downstream signaling pathways that are impacted by the absence of this gene, thus providing invaluable insights in both basic and applied research contexts.

Scientifically, the ability to study NAA40-deficient cells is essential for elucidating its role in diseases like cancer, where aberrant gene regulation can lead to uncontrolled proliferation and survival of tumor cells. Furthermore, these knockout cell lines are invaluable for the development of novel therapeutic strategies, as they serve as platforms for drug discovery and the testing of compounds that target the molecular mechanisms involving NAA40.

What sets NAA40 Gene Knockout Cell Lines apart from traditional gene editing technologies is their robustness and reproducibility. Unlike transient transfection approaches, these stable cell lines offer consistent performance across experiments, enabling researchers to yield reliable data that drive innovation in their work. Additionally, they are readily compatible with high-throughput screening applications, thereby streamlining the experimental workflow.

For scientists and clinicians engaged in cutting-edge research or therapeutic development, NAA40 Gene Knockout Cell Lines are an essential tool that promises to accelerate discovery and enhance understanding of pivotal biological processes. By providing reliable and validated models, our offering supports your exploration of gene function and its implications in health and disease.

Our company is dedicated to advancing the field of genomics and cellular biology, offering high-quality products that are backed by robust scientific validation and expertise in gene editing technologies. Together, let’s pioneer the future of biological research with precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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