Gene: MXD3
Official Full Name: MAX dimerization protein 3provided by HGNC
Gene Summary: This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25475 | MXD3 Knockout cell line (HeLa) | Human | MXD3 | 1:3~1:6 | Negative | Online Inquiry |
KO25476 | MXD3 Knockout cell line (HCT 116) | Human | MXD3 | 1:2~1:4 | Negative | Online Inquiry |
KO25477 | MXD3 Knockout cell line (HEK293) | Human | MXD3 | 1:3~1:6 | Negative | Online Inquiry |
KO25478 | MXD3 Knockout cell line (A549) | Human | MXD3 | 1:3~1:4 | Negative | Online Inquiry |
MXD3 Gene Knockout Cell Lines are genetically engineered mammalian cell lines in which the MXD3 gene has been inactivated, allowing researchers to study the biological effects and pathways associated with the loss of this gene. The MXD3 gene encodes a member of the MAD transcription factor family, which plays a pivotal role in regulating cellular growth, differentiation, and apoptosis. By utilizing these knockout cell lines, scientists can elucidate the precise mechanisms by which MXD3 contributes to various cellular processes and disease states, including certain cancers.
The primary function of MXD3 is as a transcriptional repressor, modulating gene expression in response to various signaling pathways. In knockout models, the absence of MXD3 provides a unique platform to understand its regulatory impact on genes involved in tumorigenesis and other critical physiological processes. Researchers can leverage these insights to investigate potential therapeutic targets and develop new treatment strategies.
The scientific importance of MXD3 Gene Knockout Cell Lines spans across multiple applications in basic and applied research. These cell lines serve as valuable tools for investigating the molecular underpinnings of cancer biology, metabolism, and cell signaling pathways. In clinical settings, they offer potential avenues for drug testing and biomarker discovery, ultimately aiding in the development of personalized medicine approaches.
What sets our MXD3 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility in gene targeting, ensuring that researchers can achieve consistent and reliable results. Additionally, our lines undergo rigorous validation processes, providing confidence in the integrity and performance of the product.
For researchers and clinicians, the value of the MXD3 Gene Knockout Cell Lines lies in their ability to facilitate novel discoveries and improve translational research outcomes. This product empowers users to deepen their understanding of gene function and its implications in disease, enhancing the potential for groundbreaking therapies.
At our company, we pride ourselves on our commitment to innovation in genetic engineering and our expertise in providing high-quality biological products tailored to the needs of the scientific community. Our ongoing focus on research excellence ensures that we remain at the forefront of advancements in gene technology.
Please note that all services are for research use only. Not intended for any clinical use.
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