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MTA3 Knockout Cell Lines

Gene: MTA3

Official Full Name: metastasis associated 1 family member 3provided by HGNC

Gene Summary: Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in chromatin remodeling and negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of NuRD complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15993 MTA3 Knockout cell line (HeLa) Human MTA3 1:3~1:6 Negative Online Inquiry
KO15994 MTA3 Knockout cell line (HCT 116) Human MTA3 1:2~1:4 Negative Online Inquiry
KO15995 MTA3 Knockout cell line (HEK293) Human MTA3 1:3~1:6 Negative Online Inquiry
KO15996 MTA3 Knockout cell line (A549) Human MTA3 1:3~1:4 Negative Online Inquiry

Background

MTA3 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the MTA3 gene, which plays a critical role in cellular pathways associated with cancer progression and stem cell maintenance. In these cell lines, the MTA3 gene has been precisely disrupted using CRISPR-Cas9 technology, allowing researchers to evaluate the functional implications of MTA3 loss on various biological processes such as proliferation, differentiation, and apoptosis.

These knockout cell lines operate by creating a stable, controlled environment that enables the observation of phenotypic changes and molecular alterations following MTA3 gene disruption. This mechanism allows for the dissection of pathways influenced by MTA3, providing valuable insights into the gene's role in oncogenesis and stem cell dynamics. Researchers can conduct experiments to assess tumorigenicity, evaluate therapeutic interventions, or explore gene regulatory networks, making these cell lines indispensable for advancing our understanding of cancer biology and stem cell research.

The scientific importance of MTA3 Gene Knockout Cell Lines extends to both basic and applied research settings. In a clinical context, insights gained from studies utilizing these cell lines could contribute to the development of novel therapeutic strategies aimed at targeting MTA3-related pathways and could further represent a step towards personalized medicine approaches for specific cancer types.

What sets MTA3 Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability, allowing researchers to achieve reproducible results that are crucial for validation of hypotheses. Additionally, these cell lines come with comprehensive documentation and support, ensuring ease of use and integration into ongoing research projects.

For researchers, clinicians, and biotechnology companies, the value of MTA3 Gene Knockout Cell Lines lies in their ability to provide a reliable platform for studying cancer biology and the molecular mechanisms underpinning disease. By employing our MTA3 Gene Knockout Cell Lines, users will harness the power of precision genetics to enhance their research outcomes. Our company is committed to delivering state-of-the-art biological products, backed by extensive expertise in genetic engineering and cell biology, enabling scientists to drive innovation and discovery in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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