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MRGPRF Knockout Cell Lines

Gene: MRGPRF

Official Full Name: MAS related GPR family member Fprovided by HGNC

Gene Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in nuclear membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30505 MRGPRF Knockout cell line (HeLa) Human MRGPRF 1:3~1:6 Negative Online Inquiry

Background

MRGPRF Gene Knockout Cell Lines are specialized biological tools engineered to lack the MRGPRF gene, which encodes for the Mas-related gene member F receptor. This receptor is primarily involved in nociception, the body’s detection of harmful stimuli. By creating knockout cell lines that lack functional MRGPRF, researchers can rigorously study the gene's role in pain signaling pathways and its implications in various disease states, particularly those related to chronic pain and inflammatory responses.

The key function of these cell lines is to provide a controlled environment in which the effects of MRGPRF absence can be analyzed. By utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to investigate the downstream signaling cascades and biochemical mechanisms that our bodies engage in during pain modulation and sensory perception. Such a precise tool is invaluable for understanding the complexities of pain mechanisms, paving the way for more effective pain management therapies.

The scientific importance of MRGPRF Gene Knockout Cell Lines extends into both fundamental research and clinical applications, making them crucial for drug discovery processes aimed at developing novel analgesics or therapeutics for pain-related disorders. These cell lines enable comprehensive screening of therapeutic agents, allowing researchers to observe the effects of potential medications in a targeted genetic background.

Compared to traditional cell lines or animal models, MRGPRF Gene Knockout Cell Lines provide a higher level of specificity and reproducibility, allowing for clearer interpretations of data regarding the MRGPRF receptor’s role. This specificity not only accelerates the research process but also enhances the reliability of data generated in preclinical studies.

For researchers and clinicians, the availability of these knockout cell lines minimizes experimental variability and maximizes the potential for translational research, leading to applicable innovations in pain management and treatment protocols.

Our company prides itself on its commitment to advancing science through high-quality, innovative biological products. With expertise in genetic engineering and a deep understanding of cellular biology, we provide essential tools that empower researchers to push the boundaries of their investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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