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MPV17L2 Knockout Cell Lines

Gene: MPV17L2

Official Full Name: MPV17 mitochondrial inner membrane protein like 2provided by HGNC

Gene Summary: Involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrial inner membrane. Part of mitochondrial large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24645 MPV17L2 Knockout cell line (HeLa) Human MPV17L2 1:3~1:6 Negative Online Inquiry
KO24646 MPV17L2 Knockout cell line (HCT 116) Human MPV17L2 1:2~1:4 Negative Online Inquiry
KO24647 MPV17L2 Knockout cell line (HEK293) Human MPV17L2 1:3~1:6 Negative Online Inquiry
KO24648 MPV17L2 Knockout cell line (A549) Human MPV17L2 1:3~1:4 Negative Online Inquiry

Background

MPV17L2 gene knockout cell lines are engineered cellular models specifically designed to study the effects of MPV17L2 gene deletion on cellular metabolism and function. This precisely crafted biological tool enables researchers to investigate the role of MPV17L2 in various physiological and pathological contexts. By utilizing CRISPR/Cas9 technology, these knockout cell lines provide a reliable system for examining gene function and its impact on cellular pathways.

The primary functionality of MPV17L2 gene knockout cell lines lies in their ability to delineate the biochemical pathways associated with mitochondrial dynamics, reactive oxygen species (ROS) generation, and the cellular stress response. By observing the phenotypic changes and metabolic adaptations that occur following the knockout, researchers gain insight into the gene's role in mitochondrial homeostasis, potentially linking it to broader implications in age-related diseases and metabolic syndromes.

Scientifically, these knockout cell lines hold significant value in both research and clinical applications. They serve as pivotal models for elucidating the mechanisms of diseases such as Barth syndrome and other mitochondrial disorders. Furthermore, they can be employed for drug discovery and testing, particularly for compounds targeting mitochondrial function and repair pathways.

A key advantage of MPV17L2 gene knockout cell lines over alternative models is their specificity, efficiency, and reproducibility. The precision of CRISPR/Cas9 technology means that researchers have a targeted approach to studying gene function without the off-target effects commonly seen with other methods such as RNA interference. Additionally, our cell lines are rigorously validated for stable gene alteration and functional consistency, ensuring reliable results across experiments.

For researchers and clinicians seeking to gain comprehensive insights into mitochondrial biology and its implications in disease, MPV17L2 gene knockout cell lines represent an invaluable asset. By leveraging these advanced models, users can drive forward their research in a competitive landscape, ultimately contributing to innovations in therapeutic strategies.

Our company is committed to providing high-quality biological tools, and our expertise in genetic engineering ensures that each product—like the MPV17L2 gene knockout cell lines—is developed using the latest scientific advancements, to meet the needs of the modern research community.

Please note that all services are for research use only. Not intended for any clinical use.

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