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MPP3 Knockout Cell Lines

Gene: MPP3

Official Full Name: MAGUK p55 scaffold protein 3provided by HGNC

Gene Summary: This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36572 MPP3 Knockout cell line (HeLa) Human MPP3 1:3~1:6 Negative Online Inquiry
KO36573 MPP3 Knockout cell line (HCT 116) Human MPP3 1:2~1:4 Negative Online Inquiry
KO36574 MPP3 Knockout cell line (HEK293) Human MPP3 1:3~1:6 Negative Online Inquiry
KO36575 MPP3 Knockout cell line (A549) Human MPP3 1:3~1:4 Negative Online Inquiry

Background

MPP3 Gene Knockout Cell Lines are specialized cellular models designed to advance the study of the MPP3 gene's functions and implications in various biological processes. These cell lines have been meticulously engineered to exhibit a complete knockout of the MPP3 gene, thereby providing a unique platform for researchers to explore the gene's role in cellular signaling, development, and potential involvement in diseases such as cancer and neurodegeneration.

The key functions of MPP3 Gene Knockout Cell Lines stem from their ability to elucidate the biological consequences of MPP3 loss. By observing these modified cell lines, scientists can investigate the downstream effects on signaling pathways, gene expression, and cellular morphology, which may contribute to a deeper understanding of pathophysiological mechanisms. The knockout approach effectively simulates specific gene loss, allowing for targeted studies and comparative analyses with wild-type cells.

The scientific importance of these cell lines is substantial, with applications spanning fundamental research, drug discovery, and therapeutic development. In clinical settings, understanding the role of MPP3 can provide insights into patient-specific therapies and personalized medicine, particularly in cancers where this gene may play a significant role in tumor progression or resistance to treatment.

What sets MPP3 Gene Knockout Cell Lines apart from alternative models is their rigorously validated gene disruption, ensuring high specificity and reproducibility in experimental outcomes. Additionally, they are compatible with a variety of assays, including high-throughput screenings, making them highly versatile tools for modern research needs.

For researchers and clinicians, these cell lines represent an invaluable asset for investigating gene function and therapeutic pathways, ultimately leading to more effective treatments and a deeper understanding of genetic contributions to disease. This aligns with our commitment to provide high-quality, reliable biological products, backed by extensive validation and expertise in genetic engineering. At [Company Name], we prioritize innovation and quality in our offerings, ensuring that our customers have access to cutting-edge tools that drive scientific discovery forward.

Please note that all services are for research use only. Not intended for any clinical use.

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